| Objective: Guided by the theory that“stomach discord is restless”,this study explored the pathogenesis of insomnia of spleen-qi deficiency and internal resistance of Damp-heat,observed and evaluated the clinical efficacy of Shengyang Yiwei Decoction in treating insomnia caused by spleen-qi deficiency and internal resistance of Damp-heat,hoping to broaden the clinical dialectical thinking and provide new treatment methods for insomnia of traditional Chinese medicine.Methods: In this study,70 patients with insomnia of spleen-qi deficiency and internal resistance of Damp-heat who met the inclusion criteria and did not meet the exclusion criteria were randomly divided into treatment group and control group.Among them,35 cases in the treatment group were treated with Shengyang Yiwei Decoction and Zopiclone;35 patients in the control group were treated with zopiclone alone for 4 weeks.Observe the score changes of the two groups of patients before and after treatment with PSQI scale,MFI-20 and TCM syndrome integral scale,and use SPSS25.0 statistical software for statistical analysis to evaluate the clinical efficacy and safety of the two treatment methods.Result: During the treatment period,4 cases were dropped out,including1 case in the treatment group,1 case in the control group,and 2 cases in the control group who did not take the drugs orally according to the regulations.The drop out rate was 5.7%.A total of 66 cases were actually included,including 34 cases in the treatment group and 32 cases in the control group.The observation results are as follows:1.Sleep quality efficacy: the effective rate of the treatment group was91.12%,and that of the control group was 65.62%.The treatment group was better than the control group in improving sleep quality efficacy(P<0.05).2.Daytime functional efficacy: the effective rate of the treatment group was 94.11%,and the effective rate of the control group was 68.75%.The treatment group was better than the control group in improving daytime function(P<0.05).3.In terms of curative effect of TCM syndromes: the effective rate of the treatment group was 94.11%,and the effective rate of the control group was71.88%.The treatment group was better than the control group in improving the curative effect of TCM syndromes(P;The comparison between the two groups showed that the treatment group was better than the control group in terms of improving stupor and fatigue,irritability and shortness of breath,easy to eat abdominal distension,lack of breath and lazy speech,sweating,bad wind,light thirst,and pale or pale complexion.Conclusion: Shengyang Yiwei Decoction combined with Zopiclone has remarkable effect on the treatment of spleen-qi deficiency and internal resistance of Damp-heat type insomnia.Shengyang Yiwei Decoction combined with Zopiclone and Zopiclone alone can improve the overall sleep status of patients with spleen-qi deficiency and internal resistance of Damp-heat insomnia.Shengyang Yiwei Decoction combined with Zopiclone is superior to Zopiclone alone in improving patients’ sleep status,prolonging sleep duration and improving symptoms.And can better improve the spleen-qi deficiency,internal resistance of Damp-heat type of insomnia symptoms of traditional Chinese medicine,so as to improve the quality of life of patients,and no obvious adverse reactions and toxic side effects during the drug,can be used in clinical treatment. |