| Objective: To evaluate the global and local longitudinal strain(LS)of the aortic sinus in hypertensive patients by two-dimensional speckle-tracking echocardiography(2D-STE),and to investigate the correlation between the global longitudinal strain of the left ventricle,the hemodynamic parameters of the aortic sinus and the longitudinal strain of the aortic sinus.Methods: 102 patients with chronic essential hypertension admitted to our hospital from March 2020 to February 2022 were continuously collected,among which 6patients were excluded due to moderate-severe valvular disease,1 patient was excluded due to Marfan syndrome,and 5 patients were excluded due to poor image quality.Finally,a total of 90 patients were included as the hypertension group(HP group),including 55 males and 35 females.The mean age was 59.97±11.82 years.In addition,90 healthy adults excluding organic diseases and systemic chronic metabolic diseases were selected as the control group in the physical examination center of our hospital,including 55 males and 35 females,with an average age of 56.76±13.19 years old.Age,sex,height,weight,body surface area(BSA),body mass index(BMI),systolic blood pressure(SBP),diastolic blood pressure(DBP),pulse pressure(PP),heart rate(HR)and so on of HP group and control group were obtained,respectively.The diameter of aortic sinus(Sov),left ventricular ejection fraction(LVEF)and stroke volume index(SVI)were measured by conventional transthoracic echocardiography.The global longitudinal strain of left ventricle(LVGLS)and the local and global longitudinal strain of aortic sinus were measured by 2D-STE.The differences of various parameters between the HP group and the control group were compared.Pearson method was used to analyze the correlation between LVGLS,PP and SVI and the global and local strains of aortic sinus.Results:1.Compared conventional ultrasound parameters,there were no significant differences in age,sex,height,weight,BSA and BMI between control group and HP group(P >0.05).There were significant differences in SBP,DBP,PP,HR,IVS,LVPW,SVI,LVMI,SoV,STJ and AAd(P < 0.05).2.The Sov-GLS of aortic sinus in HP group(18.96±5.15)was significantly lower than that in control group(23.65±3.24),and the difference was statistically significant(P<0.05).3.The AW-LS of aortic sinus in control group(22.05±3.76)and in HP group(18.53±5.98)was significantly lower than that the PW-LS of aortic sinus in control group(25.24±4.39)and in HP group(21.09±5.47),and the differences were statistically significant(P< 0.05).4.The AVA-LS of aortic sinus in control group(22.37±4.06)and in HP group(17.26±4.62)was significantly lower than the STJ-LS of aortic sinusin in control group(24.92±3.75)and in HP group(22.36±6.65),with statistical significance(P< 0.05).5.The global longitudinal strain of the aortic sinus was positively correlated with LVGLS,SV and SVI(r = 0.480,0.212,0.224,P< 0.05),were negatively correlated with age,SBP,PP,SoV and STJ(r =-0.207,-0.415,-0.410,-0.424,-0.299,P< 0.05),but had no correlation with BSA and DBP(P>0.05).The AW-LS was positively correlated with SVI(r = 0.218,P<0.05),but the PW-LS was not correlated with SVI(P>0.05).The AVA-LS was positively correlated with SVI(r = 0.197,P< 0.05),while the STJ-LS was not correlated with SVI(P>0.05).Conclusion:1.2D-STE can effectively evaluate the global and local longitudinal strains of aortic sinus in patients with hypertension.2.The global longitudinal strain of aortic sinus was significantly reduced in hypertensive patients.There were significant differences in the local longitudinal strains between anterior and posterior walls of aortic sinus and between the valvular side of aortic sinus and the sinotubular junction side of sinus in hypertensive and healthy people.3.The global and local longitudinal strains of the aortic sinus can be affected by the global longitudinal strains of the left ventricle and the hemodynamic parameters of the aortic sinus,such as PP and SVI. |
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