| Objective : By observing the clinical efficacy and safety of laque psoriasis blood stasis syndrome through moving cupping therapy so as to provide clinical reference for the treatment of plaque psoriasis with blood stasis syndrome in the future.Method:A total of 64 patients with plaque psoriasis and blood stasis syndrome who diagnosed and met the inclusion criteria were selected in the dermatology clinic of Shijiazhuang Hospital of Traditional Chinese Medicine from September 2020 to September 2021.They were randomly divided into treatment group(32 cases)and control group(32 cases).The control group was given the basic treatment plan,namely Taohong Siwu Decoction for oral administration,Yuze barrier repairing body lotion for external use and personal care,while the treatment group was given the basic treatment plan of the control group plus walking cupping therapy.The treatment plan of the two groups was 4 weeks as a course of treatment,and the observation period was 1 course of treatment.Observation indicators:(1)General information: including the patient’s name,gender,age,telephone number,ethnicity,work,long-term residence,family history,smoking history,drinking history,physical activity,eating habits,menstrual history,triggering and aggravating factors,test results,etc.related information;(2)Efficacy indicators: Psoriasis area and disease severity index(PASI score),individual symptoms of skin lesions(including area,erythema,infiltration and scaling),TCM syndrome scores,skin disease scores in the two groups before and after treatment The data and changes of the quality of life index(DLQI score);(3)the efficacy index of the two groups of patients;(4)At the same time,adverse events were recorded during the clinical observation.After the observation,SPSS Statistics 26.0 software was used for statistical analysis of the data.Result:(1)Psoriasis Area and Severity Index(PASI): The PASI scores of the two groups of patients after treatment were significantly lower than those before treatment,and the difference within the group was statistically significant(P<0.05).Compared the results between the two groups,the difference was statistically significant at 4 weeks of treatment(P<0.05).(2)Skin lesion area score: The skin lesion area scores of the two groups of patients after treatment were significantly decreased compared with before,and the difference within the group was statistically significant(P<0.05).Compared the results between the two groups,the difference was statistically significant at 4 weeks of treatment(P<0.05).(3)Skin lesion erythema score: After treatment,the skin lesion erythema scores of the two groups were significantly decreased compared with before,and the difference within the group was statistically significant(P<0.05).Compared the results between the two groups,the difference was statistically significant at 4 weeks of treatment(P<0.05).(4)Skin lesion infiltration score: The skin lesion infiltration scores of the two groups of patients after treatment were significantly decreased compared with before,and the difference was statistically significant within the group(P<0.05).Compared the results between the two groups,the difference was statistically significant at 4 weeks of treatment(P<0.05).(5)Desquamation score of skin lesions: After treatment,the scale score of skin lesions in the two groups decreased significantly compared with that before treatment,and the difference within the group was statistically significant(P<0.05).Results there was no significant difference between the two groups at 4 weeks of treatment(P > 0.05).(6)TCM syndrome scores: After treatment,the TCM syndrome scores of the two groups were significantly decreased compared with before,and the difference within the group was statistically significant(P<0.05).Compared the results between the two groups,the difference was statistically significant at 4 weeks of treatment(P<0.05).(7)Dermatology life quality index score(DLQI): After treatment,the score of skin disease quality of life index in the two groups decreased significantly compared with that before treatment,and the difference within the group was statistically significant(P < 0.05).There was significant difference between the two groups at 4 weeks of treatment(P < 0.05).(8)After one course of treatment,the total effective rate of the treatment group was 90.0%;The total effective rate of the control group was 80.65%,and the difference was statistically significant(P < 0.05).(9)Safety evaluation: The incidence of adverse reactions was 3.33%(1/ 33)in the treatment group and 0.00% in the control group,with no significant difference(P > 0.05).Conclusion : 1.Cupping therapy can significantly improve the psoriatic cheek,lesion area,erythema and infiltration degree of plaque psoriasis patients with blood stasis syndrome.2.Cupping therapy can improve the quality of life of patients with plaque psoriasis with blood stasis syndrome,and the treatment is safe,which is worthy of clinical application. |
