Acute Effects Of Different Forms Of Exercise On Arterial Function In College Students

Research Background: In recent years,the incidence of Cardio vascular disease(CVD)has been increasing year by year,which has become the leading cause of death in our country.The injury of arterial function is closely related to the morbidity and mortality of CVD.Regular exercise can improve arterial function.At present,the incidence group of CVD tends to be younger,and there is a difference between the sexes.It is not clear whether different forms of exercise have different effects on artery function in younger age groups,and whether the effects differ between the sexes.Research purposes: This study mainly analyzed the acute effects of exhaustive exercise,aerobic exercise,resistance exercise and combined exercise(aerobic combined resistance)on arterial function,hemodynamics and other indicators and the differences between the sexes,and further analyzed the potential physiological mechanism causing the changes.Research method: 31(15 males,16 females;Age: 23±4 years)Subjects signed subject informed consent form to participate in this study.Subjects with hypertension and known cardiovascular and metabolic diseases were excluded.(1)The maximum oxygen uptake(VO2max)and maximum heart rate(HRmax)of the subjects were measured by cardiopulmonary function tester(model: Cosmed k5)and running table.(3)1RM of subjects’ quadriceps,triceps and rectus abdominis was measured using the isokinetic muscle motor Ability Test System(Model: Biodex 4).(4)The heart rate,hemodynamic indexes and central and peripheral pulse wave data of subjects in quiet state and after exercise were measured by automatic blood pressure measuring instrument and pulse wave analyzer(Model: Sphygmo Cor).(5)Color Doppler ultrasound(model: Aloka F37)was used to measure the morphological and functional indicators of the central and peripheral arteries and the left ventricle of the subjects at rest and after exercise.A total of 4 exercise interventions were performed: exhaustive exercise,aerobic exercise,resistance exercise and combined exercise.The interval between two tests for each subject was 48 h ~ 2 weeks.Central and peripheral blood pressure,pulse wave conduction velocity(PWV),augmentation index(AIX@75%),mitral valve E-wave peak velocity(ev),mitral valve A-wave peak velocity(av)and e V/a V were measured at three time points before exercise,30 min after exercise and 60 min after exercise.Research result:(1)Blood flow dynamic indicators: The central and thermometer SBP,DBP,PP,and MAP,and P1,and AP have significant differences in the form of motion and time(P <0.05).Compared with before exercise,60 minutes after exercise and 60 min after exercise,the central and mortar arterial PP decreased significantly(P <0.05),and the central PP of the aerobic movement decreased significantly(P <0.05);60 minutes after exercise,exhausted after exercise,exhausted,exhausted The central PP of the movement decreased significantly(P <0.05),and the SBP of the aerobic mobilization of the aerator of the mortal mobility decreased significantly(P <0.05).(2)Arterial stiffness indicators: The significant differences between the lower limbs F-A PWV and TPR have the form of motion form and time interaction(P <0.05),while the central C-F PWV and the upper limb C-R PWV do not have a significant difference in motion form and time interaction.30 minutes after resistance to resistance,F-A PWV is significantly higher than the level before exercise(P <0.05).(3)Differences between genders: There were significant differences in the changes of central SBP after resistance exercise and combined exercise,c-f PWV after exhaustive exercise and f-a PWV after exhaustive exercise and combined exercise(P < 0.05).Central SBP at 30 min after resistance exercise and C-F PWV at 30min after exhaustive exercise were significantly increased in male(P < 0.05),while f-a PWV at 30 min after exhaustive exercise and combined exercise was significantly decreased in male(P < 0.05),but there was no significant difference in female(4)Correlation analysis: f-a PWV was negatively correlated with e V(P=0.000,r=-0.178).f-a PWV was negatively correlated with e V/a V(P=0.006,r=-0.141).f-a PWV was positively correlated with baseline SBP(P=0.031,r=0.389).Conclusions:(1)Acute exercise can significantly reduce central and peripheral pulse pressure.Blood pressure recovered more quickly after aerobic and combined exercises than after exhaustive and resistance exercises,both central and peripheral.Systolic blood pressure and diastolic blood pressure increased after exercise,and the change of blood pressure after resistance exercise was different between the sexes,and the increase of blood pressure was more significant in men.The higher BP after exercise may be due to HR-mediated increase in CO.(2)Acute exercise can reduce arterial stiffness and total peripheral vascular resistance.Exercise significantly improved lower limb arterial stiffness,but had no significant effect on central and upper limb arterial stiffness.Resistance exercise can increase femoral artery stiffness,while exhaustive exercise and combined exercise can reduce femoral artery stiffness.The reduction degree of femoral artery stiffness in male was greater than that in female.(3)The change of left ventricular diastolic function may be an important factor causing the difference of lower limb arterial stiffness after different forms of exercise.Lower limb arterial stiffness after exercise may be associated with enhanced left ventricular diastolic function.In both sexes,the greater decrease in lower limb arterial stiffness after exercise in men may be due to the higher SBP in the quiet state.