Clinical Observation On The Treatment Of Chronic Pelvic Pain From Sequelae Of Pelvic Inflammatory Disease Treated By Queyanling Prescription

Objective:To observe the clinical effect of Queyanling prescription combined with enema in the treatment of chronic pelvic pain following sequelae of pelvic inflammatory disease of kidney deficiency and blood stasis type.Method:Sixty-four patients with chronic pelvic pain,sequelae of pelvic inflammatory disease,who met the inclusion criteria and were treated in the gynecological department of Qinhuangcity Hospital of Traditional Chinese Medicine from December 2021 to December 2022 were selected as the study objects,and randomly divided into the treatment group and the control group with 32 patients in each group.Treatment group was given Que Yanling formula oral combined with enema for 3 menstrual cycles: Que Yanling formula concentrated granules,1 bag each time,once in the morning and once in the evening;Queyanling prescription herbal decoction,1 bag(100ml)each time,enema once every night before going to bed,menstrual period suspended.The control group was given Levofloxacin tablets combined with metronidazole tablets for 3 courses of oral treatment: Levofloxacin tablets,0.5g/ time,once/day;Metronidazole tablets,0.4g/ time,twice/day,were taken orally 3 days after menstruation was clean,and 14 days were taken as a course of treatment,with 1 course of treatment per menstrual cycle and 3consecutive courses of treatment.The serum CA125,pelvic effusion volume,TCM syndrome score,local sign score,pelvic pain VAS score,comprehensive score and safety observation index of the two groups were observed before and after treatment,and the clinical efficacy of the two treatment methods were compared.The patients were followed up for 1month after the end of treatment to observe the recurrence of patients.Results:Before treatment,the baseline of age,course of disease,serum CA125,depth of pelvic effusion,TCM symptom score,local sign score,pelvic pain VAS score and comprehensive score of the two groups were consistent(P>0.05).The results after treatment are as follows:1.Comparison of serum CA125: Serum CA125 was decreased in both groups,and the effect of treatment group was more significant(P < 0.05).2.Comparison of the amount of pelvic effusion: the amount of pelvic effusion was reduced in both groups,and the effect was more significant in the treatment group(P < 0.05).3.Comparison of TCM syndrome scores: TCM syndrome scores of both groups were reduced,and the effect of treatment group was more significant(P < 0.05).4.Comparison of local signs scores: The scores of local signs in both groups were reduced,and the effect in the treatment group was more significant(P < 0.05).5.Comparison of pelvic pain VAS scores: the pelvic pain VAS scores of the two groups were decreased,and the effect of the treatment group was more significant(P < 0.05).6.Comparison of comprehensive scores: The comprehensive scores of both groups were decreased,and the effect of treatment group was more significant(P < 0.05).7.Comparison of the curative effect of TCM syndrome: Compared between the two groups,the curative effect of TCM syndrome in the treatment group(96.77%)was higher than that in the control group(83.87%),and the curative effect of TCM syndrome in the treatment group was more significant(P < 0.05).8.Comparison of curative effect of local signs: The curative effect of local signs in the treatment group(93.55%)was higher than that in the control group(83.87%),and the curative effect of local signs in the treatment group was more significant(P < 0.05).9.Comparison of comprehensive efficacy: Compared between the two groups of comprehensive efficacy,the treatment group(96.77%)was higher than the control group(80.65%),and the comprehensive efficacy of the treatment group was more significant(P < 0.05).10.No abnormalities were observed in the safety indexes of the two groups before and after drug treatment.11.Comparison of recurrence: Within 1 month after treatment,the recurrence rate of the two groups was lower in the treatment group(3.23%)than in the control group(22.58%),and the recurrence rate in the treatment group was lower than that in the control group(P < 0.05).Conclusion:The Queyanling prescription combined with enema has advantages in reducing the serum CA125,the amount of pelvic effusion,the VAS score of pelvic pain,and improving the TCM syndrome and local signs,and the clinical efficacy is superior to the oral conventional western medicine,with high safety and low recurrence rate,so it has a good clinical application prospect.