| Objective:With the progress of society and the continuous improvement of living standards,people’s diet structure and lifestyle have changed,and the incidence of cardiovascular and cerebrovascular diseases in China has also increased year by year.Existing studies have shown that the occurrence of cardiovascular and cerebrovascular diseases is closely related to blood pressure,blood sugar,blood lipid and other risk factors for cardiovascular and cerebrovascular diseases.This study aims to explore the correlation between triglycerides and blood glucose in middle-aged and elderly patients with hypertension in rural areas of Anqing City,and analyze the factors that may affect the correlation between the two,so as to provide basis for better control of blood lipids and blood glucose in patients with hypertension,and provide targeted opinions and suggestions on the prevention and control of abnormal blood glucose and blood lipid,which is of great significance for reducing the incidence of cardiovascular and cerebrovascular diseases in middle-aged and elderly patients.To provide ideas and effective health guidance for the prevention and treatment of cardiovascular diseases.Method:This study was designed as a cross-sectional study,and the current situation study was conducted using simple random sampling from June 2020 to September2020.Yuexi County,Anqing City was selected as the research base,and then 7townships(Hot Spring Town,Maojianshan Township,Hetu Town,Laipang Town,Paradise Town,Lianyun Township and Xiangguo Township)were randomly selected from 24 townships in Yuexi County,and 30%of the hypertension patients registered in each township were randomly selected according to the list of hypertension patients registered in basic public health service projects.Physical examination,questionnaires,and biochemical tests.SPSS 25.0 software was used for statistical analysis.The counting data were expressed as frequency and composition ratio,and theχ~2test was used to compare the differences between groups.Binary logistic regression and smooth curve fitting were used to visualize the relationship between triglycerides and blood glucose.Further subgroup analyses and interaction tests were performed to assess potential variables affecting triglyceride and glycemic correlations.Both sides were tested,and the inspection levelα=0.05.Results:(1)Basic information of the research objectIn male population,there were 1004(86.1%)patients with triglyceride<1.7mmol/L,162(13.9%)patients with triglyceride≥1.7mmol/L,1040(86.1%)patients with blood glucose<6.1mmol/L.There were 126(10.8%)patients with blood glucose≥6.1mmol/L.In female population,there were 970(82.7%)patients with triglyceride<1.7mmol/L,203(17.3%)patients with triglyceride≥1.7mmol/L,and 978(83.4%)patients with blood glucose<6.1mmol/L.There were 195(16.6%)patients with blood glucose≥6.1mmol/L.Male alcohol consumption rate(42.1%),smoking rate(49.5%),current frequency of physical exercise(29.9%);Among women,rates of alcohol consumption(12.6%),smoking(15.6%),and current rates of physical activity(23%).(2)Logistic regression analysis of triglyceride and blood glucoseGLU was included in Logistic regression as the dependent variable,TG was divided into 3 groups according to the clinical critical value as the independent variable,the group with the lowest TG(<1.7mmol/L)was used as the control group,and statistically significant factors in the univariate analysis were used as adjustment variables for regression analysis.For each 1 mmol/L increase in TG,the risk of abnormal GLU increased by 0.337 times(OR=1.337),and compared with the lowest group(<1.7mmol/L),The risk of abnormal GLU increased 1.036 times(OR=2.036 times)and1.731 times(OR=2.731)in patients with elevated TG edge group(1.7 mmol/L≤TG<2.3mmol/L)and increased TG edge group(≥2.3 mmol/L),respectively,and the difference was statistically significant(P<0.05).This was the same for men and women.(3)Stratified analysis of triglyceride and blood glucoseIn the stratification of BMI and years of hypertension,patients with elevated triglycerides(≥2.3mmol/L)had higher risk of abnormal blood glucose than those with normal triglycerides(<1.7mmol/L),and the difference was statistically significant(P<0.05).In addition,BMI,years of hypertension and triglyceride had a synergistic effect on the risk of abnormal blood glucose(interaction P<0.05).Conclusion:(1)The abnormal rates of triglyceride and blood sugar in women were higher than those in men.Women have higher rates of abnormal systolic blood pressure than men,men have higher rates of abnormal diastolic blood pressure than women,and men have higher rates of alcohol consumption,smoking,and current physical activity.(2)Patients with hypertension with abnormal blood glucose have a higher rate of BMI,triglycerides,systolic blood pressure,total cholesterol,high-density lipoprotein,low-density lipoprotein,alanine aminotransferase,and aspartate aminotransferase;Patients with normal blood sugar had higher rates of smoking and drinking,and patients with abnormal blood sugar had more participation in physical exercise.(3)Blood glucose is positively correlated with triglyceride,and with the increase of triglyceride,the risk of abnormal blood glucose increases gradually.(4)There is an interaction between BMI and triglyceride,and abnormal BMI and elevated triglyceride have a synergistic effect on the increased risk of abnormal blood glucose.(5)There is an interaction between the age of hypertension and triglyceride.When the age of hypertension is 6-10 years,the triglyceride increases and the risk of abnormal blood glucose is the highest. |
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