Acupoints Selection Rule For Acupuncture Treatment Of Lower-Limb Moter Dysfunction After Cerebral Infarction Based On Data Mining

Objective: In this study,the acupuncture point prescriptions recorded in the literature that met the inclusion and exclusion criteria were loaded into Microsoft Excel software,and a database of acupuncture points for acupuncture treatment of lower-limb motor dysfunction after cerebral infarction in modern clinical research literature was established to search for acupuncture treatment of lower-limb moter dysfunction after cerebral infarction.The core acupoint group,and visualize the results to provide a reference for better improving the clinical efficacy of acupuncture.Methods:In the database,the literature was retrieved with subject terms such as “acupuncture and moxibustion,acupuncture,electroacupuncture”combined with subject terms such as “cerebral infarction,ischemic stroke,ischemic stroke” and “lower limb motor,lower limb dysfunction,lower limb spasticity,foot drop,foot inversion,gait”.Documents from China National Knowledge Infrastructure(CNKI),Wanfang Database(WANFANG),VIP Database(VIP),China Biomedical Literature Database(Sino Med)Self-built databases until December 31,2022 Using acupuncture to treat cerebral infarction For the clinical research literature on lower-limb moter dysfunction,the papers were screened according to the inclusion and exclusion criteria through the combination of Note Express 3.2.0 software and manual methods,and the title,author,intervention measures,acupoint prescription and other literature information were extracted and entered into Excel to establish a prescription acupoint database and name the acupoints.Standardized processing.The frequency analysis of acupoints,meridians of acupoints,specific acupoints,and acupoints was completed in Excel,the database was imported into SPSS modeler 18.0,and the Apriori algorithm was selected to complete the analysis of association rules,and the co-occurrence network diagram of high-frequency acupoints was visualized by Cytoscape software.The cluster analysis of high-frequency acupoints was completed in SPSS 26.0.The Fruchterman-Reingold algorithm in the Gephi 0.9.2 software were used for complex network analysis and community division.Results:1.110 clinical research literatures were screened out according to the inclusion and exclusion criteria,with a total of 110 prescriptions,involving172 acupoints,with a total frequency of 1252 acupoints,including 13extra-meridian acupoints and 18 scalp acupoints,involving 14 acupoints Meridians,distributed in 5 parts of the human body,covering all specific point types.2.The top 10 acupoints are ranked in the frequency of use: Zusanli(ST30),Yanglingquan(GB34),Sanyinjiao(SP6),Hegu(LI4),Quchi(LI11),etc.;the top 10 points are ranked in the degree: Zusanli(ST30),Yanglingquan(GB34),Quchi(LI11),Hegu(LI4),Jianyu(LI15)etc.;The top 10closnesscentrality: Zusanli(ST30),Yanglingquan(GB34),Quchi(LI11),Waiguan(TE5),Baihui(GV20),etc.;3.Meridian acupoints are frequently used,and the top 3 most frequntly used meridians are: Stomach Meridian of Foot Yangming,Large Intestine Meridian of Hand Yangming,Gallbladder Meridian of Foot Shaoyang.The acupuncture points are mainly distributed in the lower extremities.Specific acupoints account for a relatively high proportion of meridian points,and he points among five-shu points are the highest-ranked specific acupoints.4.In correlation analysis,commonly used acupoint combinations are“Hegu(LI4)-Zusanli(ST30)”,“Hegu(LI4)-Quch”,“Zusanli(ST30)-Hegu(LI4)-Quchi(LI11)”,the most commonly used The combination of meridians is “Gallbladder Meridian of Foot Shaoyang-Foot Yangming Stomach Meridian”.5.In the cluster analysis,the high-frequency acupoints with a frequency of use 20 can be divided into 5 groups:the first category is Jianyu(LI15),Shousanli,Waiguan(TE5),Hegu(LI4),Quchi(LI11),Zusanli(ST30),Taichong(LR3),Jiexi(ST41),Fenglong(ST40);the second category is Baihui(GV20),Xuehai(SP10);the third category is Weizhong(BL40),Neiguan(PC6),Sanyinjiao(SP6),Yinlingquan(SP9);the fourth category is Huantiao(GB30),Fengshi(GB31),Yanglingquan(GB34);the fifth category is Xuanzhong(GB39),Qiuxu(GB40),Kunlun(BL60).6.In the network community division,38 core acupoints with the degree greater than 51 were selected,such as Zusanli(ST30),Yanglingquan(GB34),Quchi(LI11),Hegu(LI4),Jianyu(LI15),which could be divided into 5communities.Conclusion:1.Considering the frequency,degree value,betweeness centrality and closness centrality in the complex network to analyze the results,Zusanli(ST30),Yanglingquan(GB34),Hegu(LI4),Quchi(LI11),Waiguan(TE5),Jianbiao,Sanyinjiao(SP6),Taichong(LR3),and Xuanzhong(GB39)are more important in the acupuncture treatment of lower-limb moter dysfunction after cerebral infarction as the core point.2.Acupoint selection is mainly based on local acupoint selection,with emphasis on the use of specific acupoints.The acupoints for treatment are mainly based on meridians,and the Yangming meridian of hand and foot and the Shaoyang meridian of foot are often used.The combining points of the affected channel and the combining points from the upper and lower parts of the body can be used in the complete three-stage treatment process for the treatment of lower limb movement disorders after cerebral infarction.During the recovery period,acupoints located on the inside and outside of the ankle joint and knee joint can be added.3.After cluster analysis and network community partition,four clinical core acupoint categories are obtained,which were divided into replenishing and activating qi and blood-Yangming group,alleviating spasm-Shaoyang group,nourishing Yin and relaxing tendons-Yin meridian group,regulating the mind and refreshing the brain-Scalp needle group.