| Objective: The aim of this study was to investigate the correlation between indicators of kidney injury and the ambulatory arterial stiffness index(AASI)in patients with type 2diabetes..Methods: From September 2017 to September 2022,1671 patients who visited the First Affiliated Hospital of Xinjiang Medical University and completed histological examination of kidney puncture were collected.85 patients with type 2 diabetes mellitus were finally selected after strict nephelometry and divided into Diabetic Kidney Disease(DKD)and Non-Diabetic Kidney Disease(NDKD)according to the pathological findings.All indicators were collected retrospectively and analyzed statistically using SPSS27.0..Results:1.The duration of diabetes,blood creatinine,24-hour protein quantification,ACR,24-hour urine microalbumin,fasting glucose,glycosylated hemoglobin and AASI were higher in the DKD group than in the NKD group,and hemoglobin,BMI,hematocrit,eGFR,triglycerides and blood The differences were statistically significant(P < 0.05)and lower than those in the NDKD group.2.The AASI values of patients in the DKD group were greater than those in the NDKD group(0.53± 0.14 vs.0.45 ± 0.15)The difference was statistically significant(P < 0.05)and the results of multiple linear regression analysis suggested that BMI and fasting blood glucose were the influencing factors of AASI.3.No significant correlation between indicators of kidney damage and AASI in patients with type 2 diabetes(p > 0.05).4.ROC curve analysis: The area under the curve was 0.661 and the cut-off point for AASI was0.515,meaning that patients with type 2 diabetes combined with kidney injury were more likely to have DKD when the AASI was ≥ 0.515.Conclusions: Patients in the DKD group had more atherosclerosis than those in the NDKD group,and there was no significant correlation between indicators of kidney damage and AASI in patients with type 2 diabetes. |
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