Objective: In this study,IMB model-based health education was applied to patients with type 2 diabetes treated with sodium-glucose cotransporter 2 inhibitors(SGLT2i)to evaluate the effect of IMB model-based health education in preventing the occurrence of genitourinary infection symptoms from adverse drug reactions,to investigate the effect of IMB model-based health education on patients’ compliance with medication,and to analyze the risk factors for the occurrence of infection symptoms.Methods:(1)This study is a class experimental study,310 patients with type 2 diabetes mellitus who were hospitalized in the endocrine department of a tertiary care hospital in Shenyang from October 2021 to March 2022 and treated with SGLT2 i were selected and divided into the experimental group and the control group,155 cases in each group.(2)The control group used routine care,and the experimental group used health education based on the IMB model on the basis of routine care.(3)The study tools were a self-administered general information questionnaire,the genitourinary system infection symptom index to assess whether patients had symptoms of infection,and the Chinese Version of 8-item Morisky Medication Adherence Scale(MMAS-8)to assess patients’ medication adherence.After 3 months of intervention,the incidence of genitourinary system infection symptoms and medication adherence questionnaire scores were compared between the two groups,and risk factors for the occurrence of infection symptoms were analyzed.(4)All data were statistically analyzed using SPSS 26.0,and median,number of cases,and percentage were used to describe the data;data were analyzed by nonparametric test,chi-square test,and binary logistic regression analysis;the test level α=0.05,and the difference was considered statistically significant at P<0.05.Results:(1)At the end of the trial,a total of 16(5.2%)patients were fell off,including 6(3.9%)in the experimental group and 10(6.5%)in the control group,and total of 294 patients completed data collection.There was no significant difference between the general information of the two groups(P>0.05),and the MMAS-8 scores before intervention were 3.75(2.75,4.25)in the experimental group and 3.75(2.75,4.75)in the control group,with no significant difference(P>0.05).(2)After 3 months of intervention,symptoms of genitourinary system infection occurred in 10 cases(6.7%)in the experimental group and 38 cases(26.2%)in the control group,and the incidence rate of the experimental group was lower than that of the control group(P<0.05).(3)After 3months of intervention,the MMAS-8 experimental group scored 6.25(3.75,6.75)and the control group scored 4.50(3.50,5.00),and the experimental group scored higher than the control group(P<0.05).(4)The results of binary logistic regression analysis showed that gender and history of previous infections were independent risk factors for the development of genitourinary infection symptoms,with women(OR=5.11,95%CI=2.28~11.42)and patients with a history of previous infections(OR=19.33,95%CI=8.52~43.86)having a higher risk.Conclusion:(1)In a population of type 2 diabetic patients treated with SGLT2 i,health education based on the IMB model was effective in preventing the occurrence of genitourinary infection symptoms as a result of adverse drug reactions.(2)Health education based on the IMB model reduced adverse drug reactions and thus improved patient compliance with medication.(3)Women and patients with a history of previous infections should pay more attention to the prevention of genitourinary infections when treated with SGLT2 i. |