Summary Of Professor Zhao Dongkai’s Medication Rules In The Treatment Of Chronic Obstructive Pulmonary Disease At Stable Stage

Objective: Objective: To establish a case database by collecting and COPD obstructive pulmonary disease treated and treated by Professor Zhao Dongkai from November 2018 to November 2022.By means of data mining,frequency analysis,association rules,cluster analysis,etc.,combined with the theory of traditional Chinese medicine,this paper summarized the medication rules of Professor Zhao Dongkai in the treatment of COPD in the stable stage,providing inspiration and ideas for the clinical treatment of the disease.Methods: By collecting the clinical cases of chronic obstructive pulmonary disease treated and treated by Professor Zhao Dongkai from November 2018 to November 2022,typical cases were screened according to the NADal standard,patients’ basic information and prescription composition were input into Excel,and a database was established for analysis using the cloud platform of ancient and modern medical records.To summarize the medication rule of Professor Zhao Dongkai in treating COPD at stable stage.Results:1.Among the enrolled cases,141 traditional Chinese medicines were shared,with a total of 4838 times of use,and 28 of them were used more than or equal to 75 times.They were regarded as high frequency drugs.From high to low,they were poria cocos,roasted licorice,codonopsis pilosula,cassia twig,cooked ground,Chinese yam,pinellia,platycodon grandiflorum,cornus,tangerine peel,Heishun tablet,honey ephedra,atractylodes macrocephala,red peony,peach kernel,almond,alisma orientalis,dried ginger,astragalus,magnolia officinalis,cuscuta,eucommia,perilla,schisandra Asarum,Chinese wolfberry,Baibu.2.According to the statistics of drug properties,warm drugs appeared the most,1302 times,followed by mild drugs,1159 times.The top three of the five drugs from high to low are sweet medicine,bitter medicine and bitter medicine;The lung meridian was the first,with a frequency of 2427,accounting for 50.17%,followed by the spleen meridian,kidney meridian,heart meridian and stomach meridian.3.The top drug efficacy was tonifying deficiency,followed by relieving cough and phlegm and relieving asthma,and the top 8 in the order from high to low were promoting blood circulation and removing blood stasis,benefiting water and dampness,moistening intestine and defecating,lowering qi,promoting lung,clearing heat and cooling blood,calming heart and strengthening spleen.4.Association analysis showed that there were 9 groups of commonly used drug combinations,among which 2 TCM combinations were: Melephedrin-almond,Baibu--loquat leaf,red peony root-peach kernel,platycodon platycodon peel,Codonopsis codontifolia,ophiopogonata codonopsis and Asarum-Schisandra chinensis;The three TCM combinations are: Eucommia ulmoides-Cuscuta seed-wolfberry,ginger pinellia pinellia-Magnolia officinalis-Perilla.5.Six clusters were obtained by clustering analysis:(1)Ginger pinellia,magnolia officinalis,Perilla,Baibu,platycodon,tangerine peel;(2)Honey ephedra,almond,processed licorice,Astragalus,codonopsis,Atractylodes rhizoma;(3)Wolfberry,cuscuta seed,Eucommia ulmoides;(4)Dried ginger,asarum,schisandra;(5)Cassia branch,peach kernel,red peony root;(6)Poria,alisma,Danpi,cooked ground,black shun slice,yam,Cornus officinalis meat.Conclusion:1.In the enrolled cases,the drug properties were mainly warm drugs,followed by plain drugs,sweet drugs,octyl drugs and bitter drugs.The main channels of drugs are lung,spleen and kidney.2.In terms of efficacy,it is mainly composed of drugs for tonifying deficiency,relieving cough and resolving phlegm and asthma,and promoting blood circulation and resolving stasis.It is good at warming and tonifying,promoting and lowering lung qi,and promoting blood circulation and resolving stasis.While warming and tonifying,it also pays attention to the promotion and descending of lung qi,and the smooth circulation of qi and blood.3.Supervisor often treats lung distension with multiple viscera,especially the lung and kidney.The treatment is mainly based on warming,combining the patient’s constitution and disease characteristics to carry out the methods of warming,warming,warming,and warming.It focuses on tonifying the lung and kidney,warming the middle and consolidating the surface,and also on dispersing the lung and relieving asthma,relieving cough and resolving phlegm,and removing blood stasis.