Effect Of Transcranial Direct Current Stimulation On Mild Cognitive Impairment In Type 2 Diabetes Mellitus

Objective:The aim of this study was to investigate the clinical effect of transcranial direct current stimulation on mild cognitive impairment in type 2 diabetes mellitus.Methods:A total of 100 patients with type 2 diabetes mellitus and mild cognitive impairment who were admitted to Zaozhuang Municipal Hospital from June 2020 to September 2021 were retrospectively analyzed.According to the random number scale method,100 patients were divided into the control and the experimental groups according to the ratio of 1:1.The control group received conventional hypoglycemic drugs to control blood glucose level,while the experimental group received conventional hypoglycemic drugs to control blood glucose and transcranial direct current stimulation.General clinical data were collected,including gender,age,race,history of chronic diseases(hypertension,coronary heart disease),years of education(education level above junior high school),alcohol consumption,smoking,fasting blood glucose level,body mass index,and cognitive function before treatment,4 weeks,and 3 months after treatment.Montreal Cognitive Assessment(MOCA)was used to evaluate the cognitive function of the experimental group and the control group.Auditory Word Learning Test(AVLT-H)was used to evaluate memory function.Executive ability was assessed using wired tests(STT-A and STT-B).Results:1.After 4 weeks of transcranial electrical stimulation,the cognition,memory,and executive function of the experimental group were significantly improved compared with the control group.Meanwhile,there were significant differences in MOCA score,immediate recall score,long delay recall,STT-A time and STT-B time between the experimental group and the control group(P<0.05).2.Three months after the end of transcranial electrical stimulation,the experimental group was still better than the control group in cognition,memory,and executive function.Meanwhile,there were significant differences in MOCA score,immediate memory score,long delay recall score,recognition memory score,STT-A time and STT-B time between the experimental group and the control group(P<0.05).Conclusion:In conclusion,for patients with type 2 diabetes mellitus complicated with mild cognitive impairment,transcranial direct current stimulation would significantly improve cognitive function,memory function and executive function.