Chaihujia Longgu Oyster Decoction Treatment Clinical Study On Premature Ventricular Contractions(Phlegm And Fire Above Disturbance Type) Combined With Anxiety

Objective: To observe the comparison of therapeutic effects between western medicine alone and western medicine combined with Chaihu plus Longgu Oyster decoction on anxiety patients with premature ventricular beat,evaluate the safety and effectiveness of clinical application of this prescription,and discuss the therapeutic mechanism.Methods:90 patients with premature ventricular contractions and anxiety were included in the second department of cardiology.Cases meeting the criteria were randomly divided into control group and treatment group,with 45 cases in each group.The treatment group was given bisoprolol fumarate tablets combined with Chaihu Jiachanggu Muli Decoction orally,while the control group was given oral bisoprolol fumarate tablets.The treatment period of both groups was 4 weeks.The blood routine,urine routine,liver and kidney function of the patients were detected 4 weeks before and after treatment,and the results before and after treatment were compared for safety analysis.Before and after treatment,the TCM syndrome score,24-hour dynamic electrocardiogram(ECG)frequency of premature ventricular beats,self-rating anxiety scale(SAS)score and generalized anxiety disorder(GAD-7)score were recorded to judge the curative effect.Results: 1.TCM symptom scores: After treatment,the scores of TCM syndromes in the two groups were significantly decreased compared with those before treatment,and the decrease in the individual scores of anxiety and palpitations in the treatment group was significantly greater than that in the control group,and the difference was statistically significant by the rank sum test(P<0.05).better than the control group,the difference was statistically significant(P<0.05).2.Comparison of the number of premature ventricular beats 24 hours after treatment in the two groups: the number of premature ventricular beats at 24 hours after treatment in both groups decreased,and the degree of reduction in the treatment group was higher than that in the control group,and the difference was statistically significant(P<0.05).The effect of the treatment group on the number of premature beats was better than that of the control group,and the difference was statistically significant(P<0.05).3.Comparison of Generalized Anxiety Disorder(GAD-7)scores: after treatment,the scores of both groups decreased compared with those before treatment,and the decrease in the treatment group was greater than that in the control group,and the difference was statistically significant(P <0.05);4.Self-rated anxiety Scale(SAS): After treatment,the product scale scores in both groups were significantly decreased compared with those before treatment,and the decrease in the treatment group was greater than that in the control group,and the difference was statistically significant(P<0.05).The treatment group was better than the control group in relieving anxiety symptoms,the difference being There was statistical significance(P<0.05).Conclusions: 1.Bupleurum plus Longgu Oyster soup can assist western medicine to effectively reduce the incidence of arrhythmia in patients with anxiety accompanied by premature ventricular beat,relieve symptoms and reduce TCM symptom scores;2.Bupleurum plus Longbone oyster soup can assist Western medicine to effectively regulate the autonomic nervous function of patients and relieve anxiety symptoms of patients with premature ventricular beat.