| Objectives:This study seeks to provide more suitable and sensible treatment plans and a reference point for those patients with fertility requirements,by contrasting the effects of drug therapy and various surgical treatments on the second pregnancy of those with tubal pregnancy and examining associated factors.This study proposes hypotheses and anticipations for the future research direction of this disease,based on its basis.To maximize the treatment results of these patients and advance related research,optimization is essential.Methods:This study examined the second pregnancy of patients treated at the xx Hospital of Kunming Medical University from January 2016 to December 2020,collecting related medical history data and collating it.Those who had fertility requirements and met the inclusion criteria were selected as research objects(a total of 212 cases).The patients were split into two groups,one for drug treatment and the other for surgical treatment.The surgical treatment group was further divided into salpingotomy group and salpingectomy group according to different surgical methods,and divided into laparoscopic surgery group and open surgery group according to different surgical methods.Relevant data were collected by searching medical records,telephone follow-up and other methods.Compared with drug therapy and surgical therapy,different surgical methods,surgical route treatment after tubal pregnancy in the way of pregnancy,pregnancy outcome and time differences.According to the data obtained from the study,the relevant pregnancy influencing factors,such as the number of pregnancies,the number of births,the number of abortions,whether the ovarian or fallopian tube surgery,whether the history of pelvic and abdominal surgery,age and so on,were comprehensively analyzed.The data in this research subject was processed and analyzed by SPSS26.0 software.Results: 1.There was no significant difference in re-pregnancy rate between the drug treatment and surgical treatment(p>0.05),but according to the way of re-pregnancy,the re-pregnancy rate of natural pregnancy in the salpingectomy group(90.6%)was higher than that in the drug treatment group(73.5%),and the difference was statistically significant(p<0.05).2.No noteworthy disparity was observed between the drug treatment and surgical treatment groups in terms of abortion and cesarean section(p>0.05).However,the drug treatment group had a higher rate of repeat tubal pregnancy(16.3%)than the salpingectomy group(1.2%),and the rate of vaginal delivery(40.8%)was lower than that of the salpingectomy group(70.6%).Statistically,the disparity was of great importance(p<0.05).3.No noteworthy disparity in the occurrence of abortion,vaginal delivery and cesarean section was observed between the salpingotomy embryo extraction group and the salpingectomy group(p>0.05),yet the rate of recurrent tubal pregnancy in the salpingotomy embryo extraction group(8.6%)was significantly higher than the salpingectomy group(1.2%),with statistical significance(p< 0.05).4.Analysis of influencing factors of repregnancy mode of tubal pregnancy patients: Univariate analysis showed that the time of menstrual cessation,the presence of tubal and ovarian sugery in the past and the history of pelvic and abdominal surgery had an impact on whether the second pregnancy of tubal pregnancy patients was a natural pregnancy,all p<0.05.An analysis of binary logistics regression revealed whether the prior history of tubal and ovarian sugery,as well as the history of pelvic and abdominal surgery,were independent elements in determining if the pregnancy of tubal pregnancy patients was a natural one.Patients with a history of tubal and ovarian sugery had a rate of second spontaneous pregnancy 0.138 times higher than those without such conditions(95%CI 0.043-0.442),while those with a history of pelvic and abdominal surgery had a rate of second spontaneous pregnancy 0.263 times higher than those without such operations(95%CI 0.108-0.640),p < 0.05.5.Analysis of influencing factors on the repregnancy time of tubal pregnancy patients: Univariate analysis showed that the outcome of the last pregnancy and the history of pelvic and abdominal surgery had an impact on the time of repregnancy.An analysis of binary logistics regression revealed that the time of repregnancy for tubal pregnancy patients was determined by whether they had undergone pelvic and abdominal surgery.Patients with a history of pelvic and abdominal surgery had a rate of second pregnancy within one year 0.119 times higher than those without such a history(95%CI 0.029-0.499),p < 0.05.6.Analysis of influencing factors on repregnancy outcome of tubal pregnancy patients: Univariate analysis showed that the time of menstruation cessation,history of tubal and ovarian sugery,and history of pelvic and abdominal surgery had an impact on whether the repregnancy was intrauterine pregnancy.An analysis of binary logistics regression revealed whether the history of pelvic and abdominal surgery had an independent effect on the outcome of tubal pregnancy patients’ repregnancy.The intrauterine pregnancy rate in patients with a history of pelvic and abdominal surgery was 0.129 times higher than that in patients without such a history(95%CI0.032-0.525),p < 0.05.Conclusions: 1.The rate of recurrence of natural pregnancy in the salpingectomy group(90.6%)was higher than that in drug treatment group(73.5%).2.The drug treatment group exhibited a greater rate of recurrent tubal pregnancy(16.3%)than the salpingectomy group(1.2%),and the vaginal delivery rate was lower(40.8%<70.6%).Additionally,the fenestration group had a higher rate of recurrent tubal pregnancy(8.6%)than the salpingectomy group(1.2%).3.Age,mass size before treatment,blood HCG value,number of days without menstruation and pregnancy history were not the influencing factors of re-pregnancy4.Whether there is a history of tubal and ovarian sugery is an independent factor affecting the repregnancy mode of tubal pregnancy patients.The mode,time,and outcome of repregnancy in tubal pregnancy patients are all affected by the history of pelvic and abdominal surgery. |