Study On Insulin Resistance Action To NIDDM With The Therapeutic Method Of Dispelling Sputum Quickening Blood And Removing Toxin

By use of traditional theory about TCM and combination with ancient clinical experiences, this research suggests the new viewpoint that damp-heat physique is the important physique background and intrinsic becoming-sick basis of modern NIDDM through analysing the survival environment of modern person from such a brand-new angle of "the variation of crowd physique in ancient and modern" for the first time, further deduces a hypothesis: The damp-heat stagnation changes into the toxins of phlegm-damp and stasis, which impair yin. This is the pathogenesis of NIDDM. Basing on this, we proceed to deeply study the therapeutic method and recipe of dispelling sputum, quickening blood and removing toxin. According to modem medical science knowledge that insulin resistance is the basic link and notable feature leading to NEDDM, we research to concentrate on explaining the correlation between sputum, stasis, toxin and insulin resistance, and have observed the influence of recipe of dispelling sputum quickening blood and removing toxin to insulin resistance action of NIDDM mouse by means of animal experiment. Experiment result shows: it can raise insulin sensitive index obviously, improve insulin resistance, reduce the state of high blood viscosity, hypercoagulabilty and high aggregation, regulate lipid metabolism. All these confirm: For insulin resistance to NIDDM, the recipe has remarkable therapeutic effects on the receptor and post-receptor, is a effective recipe of treating NIDDM, and its therapeutic effects are comprehensive, poly-targets and poly-links. These deepen the understanding to pathogenesis of NIDDM of TCM , offer a new pathway for clinical therapy , blaze new trails and enrich the doctrines of pathogenesis and therapy.