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Research On Distributional Rule Of Types Of Syndromes And Quantitative Diagnosis On The Common Types Of Syndromes In Crowds Of Psychological Stress

Posted on:2006-02-19Degree:DoctorType:Dissertation
Country:ChinaCandidate:Y PanFull Text:PDF
GTID:1104360152997999Subject:Diagnostics of Chinese Medicine
Abstract/Summary:PDF Full Text Request
1. AimsPresently, combining with the mode of biology-emotion-sociality, the theory of psychological stress has been widely used in medical fields. The theories of seven modes of emotions and psychological stress are the same in concept to a great extend, though there still exist some differences in the era of origin, the points of views to human and the methods of demonstration. Regarding the two theories as the definition of different cultures for the same contents in essence in different eras and different medicine should be rational and they can be the reference and supplement to each other.The study takes the social crowds as the researching objects, from which we pick out the crowds of psychological stress with the methods of epidemiology on the foundation of some psychological forms in order to find out the distributional rule of the syndromes' types of Traditional Chinese Medicine (TCM). Basing on which we can carry on the research of quantitative diagnosis to the common syndromes' types of the crowds of TCM with several kinds of statistical methods. The aim of the research is trying to combine the two theories to find the mechanism and distributional rule of diseases resulted from the psychological stress and emotion and to quantize the diagnosis of syndromes further, all of which are benefit for the further research on standardization and normalization to the differentiation of symptoms and signs, the diagnosis, prevention, therapy and establishment of evaluating system of curative effects.2. Methods2.1 Researching methods of distributional rules of the types of syndromes in crowds of psychological stressTaking the social crowds as the researching objects, we picked out the crowds of psychological stress of 2870 cases, with the methods of epidemiology on the foundation of seven modern mental scales likewise SCL-90, SDS and one scale of five kinds of personalities and one scale of the messages' collection of four diagnoses of types ofsyndromes made by ourselves. We offered the relative diagnosis and established the database about the types of syndromes, the symptoms and signs to the crowds of psychological stress, at the same time, found the distributional rules of the types of syndromes on the base of the statistical essay of the database initially2.2 Methods of quantitative diagnosis of the common types of syndromes in crowds of psychological stressWe use three kinds of methods as Bayes stepwise discriminant, Logistic regression and priorities of frequencies to study the stagnation of liver-Qi syndrome, liver-Qi attacking spleen syndrome, hyperactive liver-QI attacking the stomach syndrome and deficiency of gut-QI syndrome, each of which has over fifty cases in number on the base of researching on the distributional rule of syndromes in crowds of psychological stress. Combining with the original indexes of diagnostic criteria, indexes screened by computer and indexes bonding the two kinds of above, we establish seven diagnostic modes to each of the four syndromes and achieve corresponding diagnostic or discriminative conclusions. The four types of syndromes had been studied by factor analysis of principle constituent. 3. Results and conclusions 3.1 Distributional rule of syndromes in crowds of psychological stressthe pykno-distribution of syndromes are stagnation of liver-QI, liver-Qi attacking spleen, deficiency of gut-QI, liver-QI attacking the stomach, deficiency of both heart and spleen, deficiency of heart-energy, pathogenic fire derived from stagnation of liver-QI, deficiency of YIN of both the heart and liver, stagnation of the gallbladder-QI and disturbance of phlegm, deficiency of YIN of the heart, deficiency of blood of liver and heart, deficiency of kidney-QI, imbalance between heart-yang and kidney-yin, deficiency of spleen-QI, deficiency of heart-blood, hyperpyrexia of liver, hyperactivity of cardiac fire, deficiency of kidney-Yang one by one , stagnation of liver-QI syndrome is the most . The rules as follows:(l)The distribution of the types of syndromes can be divided into two groups in general: one is the hepatocholic depression, the other is the deficiency and the first one is in majority in pykno-distribution.(2)The main focuses of these types of syndromes are in the liver (gut), heart, spleen (stomach), especially in the liver system.(3)The proportion is lower in single type of syndrome compared with the others.(4) There exist the following possibilities that why there exist some ones who didn't construct the types of syndromes: one reason is that the bodies have accommodated to the stress, the second reason is the bodies have been in the conditions of hidden syndromes oranti-syndromes and the third is that the symbols are too dispersed to constitute typical typesof syndromes.3.2 Quantitative diagnosis of common types of syndromes in crowds of psychologicalstress3.2.1 Stagnation of liver-Qi syndrome3.2.1.1 We use screening methods of three indexes to establish three kinds of discriminative modes with the Bayes stepwise discrimminant, each of which is above 92.7 percent in coincidence, 90.2 percent in sensitivity, 94.6 percent in specificity; the results are close to the information of in the group with the knife-cutting method.3.2.1.2 We use screening methods of three indexes to establish three kinds of regression model with Logistic regression, each of which is above 92.4 percent in coincidence, 92.7 percent the sensitivity, 92.2 percent in specificity.3.2.1.3 The diagnostic weigh and threshold value achieved by the method of priorities of frequencies: the diagnostic coincidence of the original diagnostic sample is above 96.1 percent. We get the diagnostic regions of different degrees from the lightest to the most serious on the foundation of above.Presentation of results: the diagnostic or discriminative modes of stagnation of liver-Qi syndrome erected by different combinations between the above-mentioned methods and indexes have favorable diagnostic and discriminative effects. Bays stepwise discriminant has better application meanings.3.2.1.4 The core indexes of stagnation of liver-Oi syndrome selected by aggregate analysis are the follows: deprementia, sigh, string-pulse, distention and pain of lower abdomen, food-taking little, tantrum, spargosis, carmoisine of the body of the tongue and hypochondrium distending pain; the main indexes are: deprementia, sigh, string-pulse, distention and pain of lower abdomen, food-taking little, tantrum, spargosis, hypochondrium distending pain, in low spirits, sentimental, vomiting and carmoisine of the body of the tongue. Both of the two kinds of indexes show the symptoms of both emotion and body and are consistent with the changing features of psychological stress-physiological function.3.2.1.5 We found twelve latent factors from twenty-six indexes of stagnation of liver-Qi syndrome by factor analysis. Each of these affects and dominates one or some indexes.3.2.2 Liver-Qi attacking spleen syndrome3.2.2.1 We use screening methods of three indexes to establish three kinds of discriminative modes with the Bayes stepwise discrimminant. Each of which is above 92.6percent in coincidence, 90.5 percent in sensitivity, 94.6percent in specificity; the results are close to the information of in the group with the knife-cutting method.3.2.2.2 We use screening methods of three indexes to establish three kinds of regression model with Logistic regression, each of which is above 95.3 percent in coincidence, 94.6 percent and 95.9 percent in sensitivity and specificity respectively.3.2.2.3 The diagnostic weigh and threshold value achieved by the method of priorities of frequencies: the diagnostic coincidence of the original diagnostic sample is 93.24 percent. We get the diagnostic regions of different degrees from the lightest to the most serious on the foundation of above.Presentation of results: the diagnostic or discriminative modes of liver-Qi attacking spleen syndrome erected by different combinations between the above-mentioned methods and indexes have favorable diagnostic and discriminative effect. Bays stepwise discriminant has better application meanings.3.2.2.4 The core indexes of liver-Oi attacking spleen syndrome selected by aggregate analysis are as follows: deprementia, hypochondrium distending pain and spargosis; the main indexes are: deprementia, hypochondrium distending pain , spargosis, anorexia, decanta immediately after the abdominal pain and the pain relieved following, in low spirits, tantrum and string-pulse. Both of the two kinds of indexes show the symptoms of both emotion and body and are consistent with the changing features of psychological stress-physiological function.3.2.2.5 We found nine latent factors from twenty-four indexes of liver-Qi attacking spleen syndrome by factor analysis. Each of these affects and dominates one or some indexes.3.2.3 Liver-QI attacking the stomach syndrome3.2.3.1 We use screening methods of three indexes to establish three kinds of discriminative modes with the Bayes stepwise discrimminant. The coincidence, the sensitivity and the specificity are all above 89.1 percent; the results are close to the information of in the group with the knife-cutting method.3.2.3.2 We use screening methods of three indexes to establish three kinds of regression model with Logistic regression, each of which is 99.1 percent in coincidence, 98.2 percent in sensitivity and 100 percent in specificity.3.2.3.3 The diagnostic weigh and threshold value achieved by the method of priorities of frequencies: the diagnostic coincidence of the original diagnostic sample is 96.36 percent. We get the diagnostic regions of different degrees from the lightest to the most serious on the foundation of above.Presentation of results: the diagnostic or discriminative modes of liver-Qi attacking stomach syndrome erected by different combinations between the above-mentioned methods and indexes have favorable diagnostic and discriminative effect. Bays stepwise discriminant has better application meanings.3.2.3.4 The core indexes of liver-Oi attacking spleen syndrome selected by aggregate analysis are as follows: deprementia, belching and carmoisine of the body of the tongue; the main indexes are: deprementia, belching, carmoisine of the body of the tongue, string-pulse, distending pain of middle region of the upper abdomen, swallow acerbity, distending pain of lower abdomen, hiccup, abdominal distention and pain, sorrowfulness and longing for crying. Both of the two kinds of indexes show the relationship between emotion and body and are consistent with the changing features of psychological stress-physiological function.3.2.3.5 We found ten latent factors from twenty-four indexes of liver-Qi attacking stomach syndrome by factor analysis. Each of these affects and dominates one to several indexes. 3.2.4. Deficiency of gut-QI syndrome3.2.4.1 We use screening methods of three indexes to establish three kinds of discriminative modes with the Bayes stepwise discrimminant, each of which is above 88.5 percent in coincidence, 78.8 percent and 98.1 percent in sensitivity and specificity respectively; the results are close to the information of in the group with the knife-cutting method.3.2.4.2 We use screening methods of three indexes to establish three kinds of regression model with Logistic regression, each of which is above 95.2 percent in coincidence, 92.3 percent in sensitivity and 98.1 percent in specificity.3.2.4.3 The diagnostic weigh and threshold value achieved by the method of priorities of frequencies: the diagnostic coincidence of the original diagnostic sample is 98.07 percent. We get the diagnostic regions of different degrees from the lightest to the most serious on the foundation of above.Presentation of results: the diagnostic or discriminative modes of liver-Qi attacking stomach syndrome erected by different combinations between the above-mentioned methods and indexes have favorable diagnostic and discriminative effect. Bays stepwise discriminant has better application meanings.3.2.4.4 The core indexes of deficiency of gut-QI syndrome selected by aggregate analysis are the follows: inability to stay alone for fear, awaken with a startle, tired and debility; the main indexes are: inability to stay alone for fear, awaken with a startle, tiredand debility, hyperarousal and insomnia, both of the two kinds of indexes show the relationship between emotion and body and are consistent with the changing features of psychological stress- physiological function.3.2.4.5 We found five latent factors from fourteen indexes of deficiency of gut-QI syndrome by factor analysis. Each of these affects and dominates one or some indexes. 3.2.5 Evaluation of calculating methodsWhen the numerical data are consistent with the Gaussian distribution, we can use the Bayes stepwise discrimination. This method can judge the functions of each index by the absolute value of standard discriminant function coefficient in discriminant and the knife-cutting method has the effect also.Logistic regression can also be used to discriminate and classify the samples and has the same function as the stepwise discriminant, but the former is more convenient for it has no strict requirement to the distribution of data.The method of priorities of frequencies is fit for the numerical data of both normal and nonnormal distribution. This method can judge the function of each index and divide them into three kinds of degrees such as the lightest, the midst and the most serious, which are benefit to the evaluation of clinic effect and have clinic utility. 3.2.6. Evaluation of index screening techniqueThe original diadynamic criteria can be regarded as the expert index, which mean to diminish the number of indexes by the re-screening of computer, with which we can fulfils more tasks of diagnosis or discrimination. These indexes are not set for the crowds of psychological stress, but the diminishment is taken under the background of crowds of psychological stress, this is why they can be used to the crowds and its also can be taken as a reference to the other crowds.Screening indexes by computer are consistent with the sample background and the crowds of psychological stress, though there exist some which are not as the same as the diagnostic criteria or textbooks, they don't go away from the pathogenesis of syndrome.The combination of the two kinds of indexes can be consistent with the traditional diagnostic criteria and take into account of the background of the crowds of psychological stress by the mathematical statistical method. That is why we think the indexes are the best screening method of syndrome diagnosis in the condition of psychological stress.The research directed by the theories of psychological stress and seven modes of emotions is to find out the distributional rule of types of syndromes in psychological stress from a big sample with the methods of epidemiology and quantitative diagnosis of common types of syndromes with several methods, which is not the same as that of before. Our...
Keywords/Search Tags:psychological stress, seven modes of emotions, quantitative diagnosis, syndrome
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