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The Expression Of IL-2 And C-Myc Gene In Injuried Tissue Of Maxillofacial Firearm Trauma

Posted on:1996-05-16Degree:DoctorType:Dissertation
Country:ChinaCandidate:J Z QinFull Text:PDF
GTID:1104360185496862Subject:Oral Sciences
Abstract/Summary:PDF Full Text Request
In the past, a lot of studies on the Gunshot wound by the spherical projectile were undertaken, whereas the type and amount of tissue disruption can be different by various projectiles. So to speak, spheres may be useful for studying the effects of blut fragments, but information from these studies is not valid when applied to wounds caused by bullets. Thus it is necessary to make a new injury model for the study of Maxillofacial trauma by projectile. In the aftermath of injury or trauma of a tissue, a complex series of reactions are executed by the host in an effort to prevent ongoing tissue damage and implement cumulative homeostatic process. Clearly, objective evaluation of the wound per se is the element essential to proper understanding and treatment of injuries caused by penetrating proectiles.Tissue trauma per se duo to mechanical injury produces significant depression of cell-mediated and humoral immunity. IL-2 is a T-cell cytokine that plays a critical role in the generation and regulation of the...
Keywords/Search Tags:Maxillofacial, Trauma, Firearm, IL—2/IL—2R, c-Myc, TNF-α, CollagenⅠ,Ⅲ, FN, Cytokine, Protooncogene, ECM
PDF Full Text Request
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