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Experimental Studies On Pathophysiologic Effects Of Repeated +Gz Exposures On Brain And Its Mechanism

Posted on:1996-02-28Degree:DoctorType:Dissertation
Country:ChinaCandidate:X Q SunFull Text:PDF
GTID:1104360185996657Subject:Aerospace Medicine
Abstract/Summary:PDF Full Text Request
Modern high performance aircraft are capable of producing acceleration in the +9 Gz range sustained for 15 -45s which may exceed the man' s physiologic tolerance. +Gz- induced loss of consciousness (G-LOC) is not only the major factor limiting man's performance, but also the main threat for flying safety. G- LOC is classically attributed to a decrease in cortical blood flow that results from a drastic decrease in cerebral perfusion pressure. Approximately 12% to 30% of U.S. Air Force and U. S. Navy pilots flying high performance aircraft experience G-LOC. These occurrences of G-LOC have resulted in 18 class A mishap. Therefore, the focus of the...
Keywords/Search Tags:acceleration, brain, adenosine triphosphate, energy charge, lactate dehydrogenase, lactic acid, blood-brain barrier, potassium, sodium, calcium, adenosine triphosphatase, brain edema, mitochondrion, nitric oxide synthase
PDF Full Text Request
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