The Diagnosis Standards To Blood Stasis And Qi Stagnation Syndrome For Angina Pectoris Based On Prescirptions Corresponding To Syndromes

Objective:To research on the clinical features and diagnosis standard of Blood Stasisand Qi Stagnation syndrome for angina pectoris, and explore and construct the clinicalefficacy evaluation system for formulas of Traditional Chinese Medicine.Methods:1. To research some clinical randomized controlled trials (RCT) by themethod of Meta-analysis, about treating angina pectoris by promoting blood and qi. Underthe guide of the theory of Prescriptions Corresponding to Syndromes, to extract thefeatures of Blood Stasis and Qi Stagnation syndrome from the reliable literature.2. To havea epidemiological study to the actual records by the retrospective clinical investigationmethod, combined Prescriptions Corresponding to Syndromes with factor analysis, and toscreen clinical characteristics.3. According to the basis of the clinical characteristicsextracted, to make the expert questionnaire. Through undertaking one round investigationby the Delphi method, to collect and quantify and extract the experts' opinion, In order todetermine the standard of diagnosis and treatment.4. To have a small sample RCT on theformulas of promoting blood and qi, in order to verify the reliability of diagnosis standard.Results:1. The results of Meta-analysis that we researched the clinical literatureabout angina pectoris RCT treatde by the method of promoting blood and qi, there were25qualified records from516clinical records, and confirmed promoting blood and qi is theeffective method.2. From the clinical retrospective survey of1033cases diagnosed asangina pectoris, we collected71cases of Blood Stasis and Qi Stagnation Syndrome, whichaccounted for6.78%of the total number of cases, stagnation of Qi and the typicalsyndrome accounted for28.2%of71cases, the other accounted71.8%. The clinical syndromes characteristics were tightness in the chest, chest pain, dizziness, headache,palpitation, etc. The primary clinical application of prescription were Xuefu ZhuyuDecoction and Danshen Decoction; the primary clinical application of hurb were Danshen,Honghua and Taoren, and the other were Sharen, Tanxiang and Chenpi.3. The results ofDelphi method showed the syndrome characteristics were chest pain, palpitations, tightnessin the chest, unsmooth pulse, dark purple tongue, and kept consistent with the results of theliterature and clinical research.Conclusion:1. The study found that the key problem of the prescription of traditionalChinese medicine clinical assessment are the clinical diagnosis and treatment standardsunified, treatment inconsistent with expression, standardized clinical tests less, to providedifficultly the convincing efficacy examples. To construct the method to establish thediagonsis standards based on combination of diseases with differentiation of syndromes,which is one of the key technology.2. This study presented the method named as "Foutsteps method", and it is proved feasible by researching the diagnosis standards of BloodStasis and Qi Stagnation syndrome for angina pectoris.3. On the basis of the clinicalresearch about the rule of treatment and syndromes, under the guidance of the theory ofPrescriptions Corresponding to Syndromes, the method has distinct characteristics of TCMfor the diagnosis standards.4. The study is presented the diagnosis standards Blood Stasisand Qi Stagnation syndrome for angina pectoris angina for the first time, and it isobviously different with the diagnosis standards of Qi Stagnation and Blood Stasissyndrome for angina pectoris about expression and construction. It enriches diagnosis andtreatment system of TCM for angina pectoris, and has the objective evaluation of treatmentof TCM and the effect of formulas, and provides a kind of reference method and idea forclinical study.