Chinese Medicine Rheumatoid Treatment Of Active Ra Experimental And Clinical Studies

Objective:To study FengShi Ning(FSN),a preparation erf traditional Chinese medicinal herd's therapeutic effect on hanrecuozazheng of rheumatoid arthritis(RA).MethodsrTake the adjunvant arthritis(AA) rats as animal model for the studying of therapeutic effect and mechanism of FSN on experimental rheumatoid arthristis(RA). And observe the therapeutic effect of FSN on the sufferers of RA.Results:FSN can inhibit secondary joints swelling and multi-arthritis evidently; FSN can raise AA rats low LTT of spleen to normal nearly emedy the disorder of Th/Ts cells balance in peripheral blood; FSN can reduce synovial immflammation and proliferation;FSN can reduce neogenetic veins.so inhibit the growth of pannus tissue and the damage of cartilage and bone by that The above effect of FSN are in proportion to its dosage. The clinic result shows that FSN can reduce stiff in the moring,swolicn and pain of joints,improve joint fun ctional conditions.Meanwhile,it can reduce serum ESR\ Mucuu CRP and rheumatoid factor liter.Conclusions:FSN has inbitibory effects on symptom and condition of experimental RA and sufferers of RA, which is better than TWP as a whole.