60-pass Pill Treatment Of Hyperlipidemia. Clt Blood Stasis Phlegm Internal Resistance Permit Multi-center Clinical Study

Hyperlipidemia has close relationship with atherosclerosis. It can lead to and promote the occurrence and development of atherosclerosis. It is a powerful and independent risk factor of cardiovascular and cerebrovascular disease. Lowing the lipid is the effective method of preventing and curing cardiovascular and cerebrovascular disease. It can improve the function of blood vessel endothelium, prevent the fragile atherosclerotic plaque to forming thrombus, delay the occurrence and progression of atherosclerosis and decline the morbidity and mortality of cardiovascular and cerebrovascular disease. In recent years,with the elevation of people's living level and high calorie ingredient such as lipid and sugar in dietary pattern increasing,the morbidity of hyperlipidemia tends to be rising.Investigations suggest that the control of dyslipidemia is bad in our country.So,how to prevent and cure hyperlipidemia has become an important study.And it has important clinical meaning to seek safe and effective lipid-lowing drugs.At present,most of effective lipid-lowing drugs are import western medicine.They are expensive.They have serious side effect and short drug action.Therefore,it has important clinical and practical worth to continue to study lipid-lowing drugs with high curative effect,low side effect and price.In recent years,using chinese medicine to prevent and cure hyperlipidemia has achieved good curative effect. Modern pharmacological research confirms that many chinese medicine has definite curative effect of lowing lipid.Using chinese medicine to low lipid is slow,but it has the characteristic of cheap and slight side effect.Hyperlipidemia belongs to the"phlegm"or"stagnated blood"category in TCM.The occurrence of hyperlipidemia has close relationship with the functional disorder of liver,spleen and kidney.It mainly refers to the four aspect:qi,blood,phlegm and stasis.The study has the idea that stagnation of liver-qi and blood stasis and endogenous retention of phlegm is the important pathogenesis of hyperlipidemia and dispersing the depressed liver-qi to promote blood flow and dissipate phlegm is the important treating method of hyperlipidemia.Qing Zhi Liu Tong Pill is composed by Cuxiangfu,Cuwulingzhi,Dahuang and Shengjiang.The whole formula has the function of regulating qi to solve stasis,promoting blood flow,eliminating phlegm.It can be used to treat patients with hyperlipidimia belonged to the syndrom of qi-stagnancy and blood stasis and endogenous retention of phlegm This study aims at observating the clinical curative effect and safety of Qingzhiliutong pill in treating patients with hyperlipidimia belonged to the syndrom of stagnation of Qi and blood and endogenous retention of phlegm in multi-center.Two parts in the thesis: document reviews and clinical research.Document reviews:First,we reviewed and summarized the progression of traditional chinese medicine (TCM) in the name, etiology, pathogenesis, curative method and prescription of hyperlipidemia in the past ten years.We proposed the problem existed in these studies and gave solutions.We also prospected the direction of studies.Then,we reviewed and summarized...