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Adiponectin And Ppar¦Ã Gene Polymorphism And Coronary Heart Disease And Its Risk Factors

Posted on:2007-10-09Degree:DoctorType:Dissertation
Country:ChinaCandidate:S X LuoFull Text:PDF
GTID:1114360185488138Subject:Internal Medicine : Cardiovascular Disease
Abstract/Summary:PDF Full Text Request
OBJECTIVE: To analyze the relationship between conventional cardiovascular risk factors and the characteristics of clinical phenotypes as well as coronary artery lesions among patients with coronary artery disease in Chongqing area.METHODS: 398 subjects were selected to be undergone coronary angiography, and according to the result of angiography result and clinical data, they were divided into three groups: coronary artery disease (CAD) group, coronary artery artherosclerosis (CAS) group and control (CT) group. A survey about conventional risk factors of those three groups was done, including smoking history, body mass index (BMI), hypertensive (HP), type 2 diabetes mellitus(T2DM), hyperlipidemia, and so on. Based on those data, the correlation between the risk factors and the clinical characteristics as well as coronary artery lesions was analyzed.RESULTS:1,Compared with CT group, the percentage of smoking history, HP, T2DM , hyperlipidemia, and family history of cardiovascular disease was higher significantly in CAD group(p<0.05,most p<0.01). In addition, men were more likely to suffer from CAD than women (P<0.05).Interestingly, there was no significant difference of BMI for these two groups.Compared with CT group, the percentage of HP and family history of...
Keywords/Search Tags:coronary artery disease, coronary angiography, risk factor, adiponectin, gene polymorphism, Coronary artery disease, Peroxisome proliferator activated receptors, high sensitivity C-reactive protein, risk factor
PDF Full Text Request
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