Inherent Rules Of Emotional Therapy For Menopausal Syndrome Based On Data Mining

Object ives:The trend of menopausal syndrome is an upward and earlier age. It has been a focus of the world's medical research that is how to alleviate symptomsand improve life quality of women with menopausal syndrome. Modern medicine had advocated that menopausal syndrome was treated by Hormone replacement therapy (HRT), but HRT have a variety of side effects, and affected the patient's compliance. It is urgent to find a treatment that is significant effect and relatively few side-effects. Non-drug therapy is becoming a focus at home and abroad, but it was mainly concentrated in psychological therapy alone or as adjuvant therapy, moreover, there is lack of a complete psychological treatment programs, and a accepted treatment in industry.The result showed that compared with placebo group, total score difference of first visit and the 4th week, first visit and the 8th week in emotional group were no significant difference (P>0.05), first visit and the 12th week in emotional group were significant difference (P<0.05); compared with TCM group, TCM and emotional group, total score difference of emotional group were no significant difference (P>0.05). On the basis of data that was collected by National Science and Technology 15 key from 2001 to 2003 and the Eleventh Five-year rolling from 2004 to 2006 in the previous issues. To research rules of menopausal syndrome, and emotional therapy for menopausal syndrome. To provide theory for the technical specifications and standards of diagnosis and treatment of emotional therapy for menopausal syndrome.Methods:Patients fulfilling the diagnostic criteria, inclusion criteria and exclusion criteria, then data integration, pre-processing, format conversion. Data were analyzed by descriptive analysis, groups were analyzed by analysis of variance, group comparison were analyzed by paired t test. To adopt cluster analysis and association rules methods for data mining. Analytical content: (1) The inherent rules of menopausal syndrome:Investigation and Analysis of emotions of Menopausal syndrom. Cluster analysis of depression, anxiety and TCM Syndrome. Association rules of emotion and the general situation, kupperman index (KI), Menopause-Specific Quality of Life (MENQOL) and traditon chinese medicine (TCM) scales. Association rules of sleep problems and somatic symptoms. (2) Internal rules of emotional therapy for menopausal syndrome: Different time points scores compared bewteen four groups of KI,MENQOL scales and TCM score table. Different time points scores compared in emotional group of KI,MENQOL scales and TCM score table before and after treatment. Efficiency Analysis of the various symptoms of each group. Association rules between efficacy and symptoms in the TCM sare table.Results:1 The inherent rules of menopausal syndrome1.1 Investigation and Analysis emotions of menopausal syndrome:(1) The frequency of anxiety and depression was respectively 89.47%,77.03%, which is he highest frequency in 17 emotions of women with menopausal syndrome.(2) There were four symptoms that Frequency of symptoms in KI and MENQOL scale was more than 80%, and Frequency of Severe symptoms of women with menopausal syndrome was more than 7%, the symptoms were insomnia, Musculoskeletal pain, fatigue, hot flushes and sweating symptoms. 1.2 Cluster analysis of depression, anxiety and TCM Syndrome:(1) Cluster analysis of depression and anxiety:Frequency of pure anxiety, anxiety and depressive symptoms, other emotions, pure depression was respectively 18%,63%,13%,6%。(2) Cluster analysis of depression, anxiety and TCM Syndrome:The frequency of total anxiety and depression in Kidney Yin deficiency Syndrome was respectively 81%,71%. The frequency of total anxiety and depression in Kidney Yang deficiency Syndrome was respectively 81%,69%.(1)lean body, Severe and moderate disease, university and college education were positively correlated with anxiety. Menopause, junior secondary education, high school education and mild disease were negatively correlated with anxiety. Appropriate body was two-way negatively correlated with anxiety. (2) Severe and moderate disease, junior secondary education, menopause and fat body were positively correlated with depression. FSH>30U/L and Menopause were two-way positively correlated with depression. High school education, premenopausal, university and college education, FSH≤30U/L were negatively correlated with depression. appropriate body was two-way negative correlated with depression.(3) Severe disease and FSH>30U/Lwas positive association rules, moderate disease and FSH>30U/L was no association rules, mild disease was positively correlated with FSH>30U/L. Severe disease and and Kidney-yin deficiency was negative association rules, moderate and mild disease were positively correlated with Kidney-yin deficiency. 1.4 Association rules of anxiety, depression and symdrome of MENQOL scale(1) Asomotor, sexual domains, and anxiety, depression were the two-way positive correlation rules.(2) Anxiety, depression and physical domains:poor spirit, changes of appearance of skin or complexion, dry skin, lack of energy, frequent urination, sleep problems, physical decline, fatigue or exhaustion, neck pain or headache, backache, muscle and joint pain, and anxiety, depression were two-way positive correlation rules. Swelling and discomfort feeling, weight gain, unable to control urination when cough or laugh, these symptoms and anxiety, depression were positive correlation rules.1.5 Association rules of anxiety, depression and symptoms of KI scale, TCM sore table:(1) There were two-way positive rules, btween palpitations, irritability, paresthesia, algopareunia symptoms of KI sale and anxiety, depression. Anxiety and urinary symptoms was two-way positive rules. Urinary symptoms and depression was not relevant rules. Crawing feeling of skin was positively correlated with anxiety and depression.(2)Gloomy complexion, tinnitus, cold feel of limbs, dizziness, constipation, knees soft, hand and foot fever, nocturia symtoms of TCM sore table were positively correlated with anxiety and depression. Depression and dry mouth, sore waist was two-way positive correlation rules.1.6 Association rules of Sleep problems and physical domains:Unable to control urination when cough or laugh, Swelling and discomfort feeling were positively correlated with sleep problems. Weight gain and sleep problems were not relevant rules. Other symptoms of MENQOL scale were positively correlated two-way rules with sleep problems.2 Internal rules of emotional therapy for menopausal syndrome2.1 Efficiency Analysis of the symptom(1) TCM score table:Compared with placebo group, total score difference of first visit and the 8th week, first visit and the 12th week in TCM group were significant difference. Total score difference of first visit and the 4th week, first visit and the 8th week, first visit and the 12th week in TCM and emotion group were significant difference. Total score difference of first visit and the 8th week, first visit and the 12th week in emotion group were significant difference.(2) KI scale:Compared with placebo group, total score difference of first visit and the 8th week in TCM group were significant difference. Total score difference of first visit and the 4th week, first visit and the 8th week, first visit and the 12th week in TCM and emotion group were significant difference. Total score difference of first visit and the 12th week in emotion group were significant difference.(3) MENQOL scale:Total score difference of four dimensions between first visit and the 12th week in four groups were no significant difference. 2.2 Total score of TCM score table, KI and MENQOL scale in different time in emotion group were compared, there was statistically significant. 2.3 Efficiency Analysis of the symptom(1) Efficiency Analysis of the symptom in MENQOL scale were more than 50% in four groups:hot flushes, spontaneous perspiration in daytime, night sweats, sleep problems, tired or exhausted, Physical decline, feel a lack of energy, lumbago, anxiety or tension, neck pain or headache, muscle and joint pain. There had also frequent urination, hypomnesia in tcm group, not satisfied with life, work smoothly in the past, depression or low mood and poor spritis in tcm and emotion group, depression or low mood, hypomnesia and a lack of patience in emotion group, work smoothly in the past in placebo group.(2) Efficiency Analysis of the symptom in TCM score table were more than 50% in four groups:sweating,irritability,hot flushes,dry mouth,insomnia,sore waist. There was hand and foot fever in tcm group, TCM and emotion group had dizzines, depression, hand and foot fever, complexion dark and gloomy. Emotion group had hand and foot fever, depression, complexion dark and gloomy, soft-knee.(3) The efficiency of each symptom in KI scale was more than 50%:there were hot flushes and sweating, excitability, insomnia, fatigue, paresthesia, muscle, bone and joint pain in four groups. There were palpitations, depression, dizziness in tcm and emotion group. There were palpitations, depression in emotion group.2.4 Association rules between symptom in TCM score table and efficacy at 12th week:Effect of treatment on efficacy from high to low:(1) Emotion Group:severe sore waist, severe sweating, moderate complexion dark and gloomy, severe hot flushes, moderate irritability, moderate insomnia, moderate hand and foot fever, moderate soft-knee.(2) TCM and emotion group:mild irritability, moderat insomnia, moderate hand and foot fever, severe irritability, severe sweating, severe hot flushes, severe depression, moderate dizzines, mild dizzines, moderate soft-knee, moderate hot flushes, moderate dry mouth, mild dry mouth, mild hand and foot fever, mild depression, mild hot flushes, moderate severe sweating, mild sore waist, moderate sore waist, mild sweating, moderate complexion dark and gloomy, mild complexion dark and gloomy, moderate depression.(3) TCM group:severe irritability, moderate hand and foot fever, moderate dry mouth, moderat insomnia, severe hot flushes, moderate sweating, severe sweating, moderate hot flushes, moderate irritability, mild sore waist.Conlusion:1 The symptoms that seriously impacted on life and work of menopausal women were hot flushes and sweating, insomnia, musculoskeletal pain, fatigue symptoms.2 the Abnormal emotions of women with menopausal syndrome were affected by many factors, such as general situation, vasomotor symptoms, somatic symptoms, sexual symptoms. The emotions were irritability, easy to grief, and anxiety, especially complex emotions. Emotions should have different grade and performance.3 The emotional therapy can not completely suitable for women with menopausal syndrome and complex emotions. According to the different grade and performance style of emotion, emotional therapy can be adjusted.