The Effect Of Bushenjiangpihuoxue Method With Postmenopausal Osteroporosis Patients On Bone Transformation

ObjectiveIn order to disuse the effects of gukang on the bone Transformation of the postmenopausal osteoporosis, The clinical observation of retrain the bone high conversion rate by Gukang and calcium, and the influence of bone forms as well as the bone absorption target. The clinical observation and comparison of the effects of preparation prevention and the treatment menopause the osteoporosis by Gukang as well as calcium, To analysis the osteoporosis occurrence mechanism as well as the Chinese medicine application mechanism, fill up the clinical data of Gukang on the bone forms and the bone absorption.MethodA total of 58 postmenopausal osteoporosis women diagnosed with the clinical examination and bone mineral density were Chosed, who were volunteered to join the clinical trials, According to the number of bone mineral density examination divided into two groups randomly, Gukang group and the control group, two group were given Publicity and education. FOR the control group were given Caltrate D film,1 #/day. GuKang Group were given to Prescription GuKang (1 dose/d) and Caltrate D film 1 #/day, the method of drug delivered was cyclic intermittent administration, which took three weeks straight, rest for 1 week. A course of 4 weeks for 6 cycles. Measured by bone mineral density and enzyme-linked immunosorbent assay before and after treatment, the level of serum Bone source alkaline phosphatases, osteocalcin, tartrate-resistant acid phosphatase, urinary deoxypyridinoline and urine creatinine, and treatment group compared with the test before and after the data, we take the bilateral side ofα<0.05 as statistically significant difference in standards. ResultAccording to statistical results suggest:GuKang group and control group in age, weight, height, body mass index, menopausal age are compared, P> 0.05, there was no significant, the bone mineral density, and the leber of serum B-ALP, BGP, TrACP, DPD excretionof both Gukang group and control group before treatment compared, P> 0.05, there was no significant, indicated that it is reasonable and comparability according to the order of selection in case of randomized number between the two groups. GuKang group and the control group after treatment bone mineral density, the level of serum B-ALP comparison, P> 0.05 there was no significant, the level of serum BGP, TrACP, DPD excretion rate comparison P<0.01 there were distinguished significant. Bone mineral density before and after treatment of Gukang was not significant, before and after treatment B-ALP, BGP, TrACP, DPD excretion was significant difference. Control group, bone mineral density before and after treatment, TrACP, DPD excretion compared, P> 0.05, not significant, B-ALP before and after treatment comparison, P<0.05, statistically significant, before and after treatment BGPP<0.01 the was distinguished significant.Conlusions1. According to bone mineral density in selected cases when the sequence number randomized feasible, Gukang group and control group in age, weight, height, body mass index, menopausal age was not statistically significant, Gukang grop and control groups before treatment bone mineral density, B-ALP, BGP, TrACP, DPD excretion rate was not statistically significant between the two groups thatthey were comparable.2. The control group before and after treatment bone mineral density, TrACP, DPD excretion rate was not statistically significant, before and after treatment, B-ALP were statistically significant. BGP concentration were significant differences in calcium therapy on bone mineral density, TRACP, DPD excretion not significant, can reduce the concentration of B-ALP and BGP levels, inhibit the bone high conversion, it can be used to prevent and treat postmenopausal osteoporosis.3. GuKang group before and after treatment no significant in bone mineral density after treatment, B-ALP, BGP, TRACP, DPD excretion was significant difference in bone GuKang group and the control group after treatment bone mineral density, B-ALP was not significant After treatment, BGP, TRACP, DPD excretion was significant difference, indicating bone health to effectively inhibit bone of high conversion rate, can promote bone formation and reduce bone resorption, in the prevention and treatment of postmenopausal osteoporosis, the effect significantly superior in the control group.