| "External disease based on internal damage of the Kidney system" is one of the common clinical diseases and belongs to deficiency pattern complicated with excessive-pathogenic patthern category, which the treatment is more difficult than simple disease caused by exogenous pathogenic factors. Kidney internal injury includes the original kidney diseases, such as:primary glomerular nephritis, nephritic syndrome, diabetic nephropathy, hypertensive nephropathy, chronic renal insufficiency, etc. "External disease based on internal damage of the Kidney system" is a holistic pathologic status, which based on these set of chronic Kidney diseases with the exogenous symptoms, rather than simple addition of chronic kidney disease and exogenous. Kidney disease has its own clinical characteristics, so External diseases based on it have also its particularity. This research is establish on the theories of external diseases based on the internal injuries, and to investigate the pattern and treatment characteristics of on diseases of Kidney system, and also it concluded the experience of adviser's clinical treatment method, on external disease based on internal damage of the Kidney system, by use of external diseases of the internal injuries theory.This paper is divided into three parts:theoretical discussion, clinical research and the conclusion.1 Theoretical discussionExternal disease based on internal damage of the Kidney system is a complicated clinical status which includes both the exogenous and the internal damage of the Kidney system with multiple etiological factors, pathogenesis and clinical manifestations. Because of the characteristics of Kidney disease, Patients are more vulnerable to exogenous pathogens attack, its clinical course different from other external diseases of the general principle and has its own special characteristics.In the early stage of kidney disease, mostly expressing on kidney deficiency, yin and yang imbalance in chronic disease, and all five organs damage. Dysfunctional in organs, body fluid metabolism disorders, blockage in qi and blood flow, flow or triple energizer interrupted, it prone to cause phlegm and stasis endogenous, systemic blood vessels stasis, qi and blood flow damaged in circulation, relevant zang-fu viscera loss its nutrient and complicated syndrome happened. In late stage, yin and yang deficiency, spleen and kidney decay, toxin stop inside, finally become life-threatening. Exogenous Kidney disease in the injured, the overall pathogenesis change is different from the simple internal injuries of Kidney disease, and it is also different from the common cold. It is original basis of yin and yang, qi and blood disorders, then lets to Lung disorder, phlegm and blood stasis block in the lung, which caused by "Lung and wei-qi impairment" and the root caused is "yin and yang imbalance". Pathological factors is complex and change easily, phlegm and blood stasis stalemate incomprehensible, zang-fu viscera, triple energizer, meridians, qi and blood are not in normal principle, blockage and difficult to hard to dredge.Patients with Kidney disease often show non-typical and atypical symptoms, In the course of disease, phlegm stasis, triple burner block and Negative catharsis can be seen, stasis is always existence. Liver stagnation can be effected, the symptoms becoming diverse and complex. It can not use a single type of general syndrome to sum up.Department of External disease based on internal damage of the Kidney system combine the Visceral Syndrome with Triple Burner Syndrome. In the Visceral Syndrome, it belongs to the lung, spleen and kidney, if in accordance with the triple burner syndrome, involves the upper, middle and lower triple burner. The transmission path in the Visceral Syndrome becomes the upper, middle and lower triple burner.Patients with Kidney disease and exogenous pathogens, symptoms are complex, multiple body organs will be involved and pathogenesis is difficult to hold. In treatment, it is necessary to benefit lung, spleen and kidney and reorganizing the triple burner. This requires to starting from triple burner organs, using reconciliation Shao Yang and Shu Li triple burner method, by adjusting the state of balance in human body, to make qi and blood smooth.2 Clinical researchPartâ… :Forward-looking and Control of study between external disease based on internal damage of the Kidney system and external disease without internal damage of the Kidney system.1. Case Source102 observation group Patients are collected from January 2009 to January 2010 in Liang-duo Jiang Professor, Dongzhimen Hospital, Consistent with diagnosis of chronic kidney disease and Acute upper respiratory tract infection.102 control group I patients were collected in Liang-Duo Jiang Professor, Dongzhimen hospital emergency station, the Sino-Japanese hospital emergency station, consistent with acute upper respiratory tract infection, and can 1:1 ratio with observation group Patients according to gender and age.102 cases of observation group patients,83 were from out-patient,19 were from wards.102 cases of control groupâ… patients,58 were from out-patient, and 64 were from emergency room. In each group, there were 35 male and 67 females, male:female= 1:1.9.2. Exogenous disease seasonal distribution of the two groups About two groups of exogenous disease season, the first was winter, spring and autumn followed, and the last was summer. Cold and dry evil are the main pathogenic factor.3. Temperature changes of two groups64 patients in the observation group had no significant increase in body temperature (accounting for 62.75% of patients in this group), only 27 people's (accounting for 26.47% of patients in this group) temperature above 38℃; In the control group I,34 patients had significantly increase in body temperatures (accounting for 33.33%of patients in this group),45 people's body temperature above 38℃(accounting for 44.12% of patients in this group).4. Exogenous disease course of two groupsPatients in the observation group with exogenous course of 8-14 days were most (50.98%), followed by 15-30 days (34.31%), and≤7 days (11.76%) and> 30 days (2.94%) were relatively least. Patients in the control group I with≤7天course were most (57.84%), followed by 8-14 days (40.20%),15-30 days at least (1.96%),> 30 days were 0.5. Changes in renal function between two groups before and after the exogenous diseaseAfter the exogenous disease, renal function in the observation group becomes lower. But in control group I was no significant changes.6. Changes of symptoms between the two groups before and after the exogenous diseaseBefore the exogenous disease, symptoms in the observation group patients were varied, these symptoms were further increase among the exogenous disease, after the exogenous disease, symptoms were still exists. In control group I, some symptoms can appear among the exogenous disease, but after the exogenous disease can disappear.7. Changes in tongue of the two groupsPatients tongue in the observation group are dark-based (including the dark, dark, dim, dark purple), tongue are tired of (including greasy, yellow and greasy) dominated; Patients tongue in control group I were red-based within 72 hours, after external disease was treatment, mainly with pink, white tongue coating are thin, thin yellow-based,8. Changes in pulse of the two groups The single pulse in the observation group are heavy, thin, string-based; in the control group I are floating, number and string-based within 72 hours, after external disease was treatment were string, moderate and mainly fine.9. Stasis in both groupsIn addition to the evidence of external diseases, deficiency of yang, deficiency of yin, deficiency of yang and yin, phlegm, blood stasis and stagnation of liver are existence in the observation group; But in the control group I, only the evidence of external diseases can be seen.Partâ…¡:Contrasting between external disease based on internal damage of the Kidney system and external disease without internal damage of the Kidney system by using theory of external diseases based on internal damage.1. Case SourceIn the observation group,39 treatment group cases collected from liang-Duo Jiang Professor's out by treating with traditional Chinese medicine,39 control groupâ…¡cases were without Liang-duo Jiang Professor treatment, but can 1:1 ratio with treatment group Patients according to gender, age and renal function. Treatment group were all from Liang-duo Jiang Professor Patient, in the control groupâ…¡7 patients were from Dongzhimen Hospital Nephrology wards,22 were from other clinics, In each group, there were 13 males and 26 females, male:female=1:2.2. TreatmentUsing study of self-control and compared with oneself before and after. Treatment group treatment by using theory of external diseases based on internal damage, combined with patient's own situation, different decoction was given different patient; control groupâ…¡without a mentor Decoction of patients, their treatment protocols were antibiotics and proprietary therapy.3. Exogenous disease course of two groupsExogenous disease course of patients with 8-14 days was maximum (66.67%),≤7 days followed (20.51%),≥15 days was the least (12.82%); control groupâ…¡exogenous disease course in patients with 8-14 days was maximum of (53.85%),≥15 days followed (38.46%),≤7 days was the least (7.69%).4. Changes in renal function between two groups before and after the exogenous disease Renal function had no difference between treatment group and control groupâ…¡before and within 72 hours of external disease, it changed after external disease. And renal function becomes lower in the control groupâ…¡.5. Changes of symptoms between the two groups before and after the exogenous diseaseWithin 72 hours, two groups of patients with similar symptoms scores, no significant difference; after external disease, patients were more significant differences associated with symptom score. After treatment, the treatment groups of patients with symptoms were alleviated, the control groupâ…¡patients with poor symptom improvement.6. Comparison of two groups of patients with medicationTreatment group are treatment by using theory of external diseases based on internal damage, Chinese herbal formula used by the main agent, according to agent frequency statistics, the top 30 flavor of traditional Chinese medicine are:Bupleurum, Scutellaria root, red peony root, astragalus, Guizhi, raw licorice, Zhimu, CARVACROL, Jiang Ban Xia, wind, Arctium, Codonopsis, paeonol, Atractylodes, Polyporus, Cooked rhubarb, Ligustrum lucidum, forsythia, san qi, Trichosanthes, honeysuckle, mulberry leaves, crane grass, fried almonds, Chrysanthemum, Angelica, mulberry leaf, red sage root, Rehmannia, Fructus real.Control groupâ…¡without a mentor Decoction of patients, greater use of antibiotics and traditional Chinese medicine, some patients were not taking any medications.3 Conclusion1. Pathogenesis of External disease based on internal damage of the Kidney system is complex, deficiency of yang, deficiency of yin, deficiency of yin and yang are the virtual, phlegm, blood stasis, stagnation are also existence.2. Internal damage of the Kidney system will extend external diseases, disease potential will hard to be cured, external diseases will increase the existing Department of internal injury of renal disease.3. Sanjiao stagnation is an important pathogenesis in external disease based on internal damage of the Kidney system, treatment should start organs triple burner, Bupleurum are used usually, About internal injury of kidney disease, we should pay attention to benefit qi and make xue live, Li Yang of gas water, spleen and stomach should be taken into account; Against the evil of exogenous drug selection and emphasis should not cold and heat. 4. The theory of external diseases based on internal damage is effective clinical medicine; it comes from clinical practice, not only inherits the essence of the diagnosis and therapy, but also absorbed the new achievements of modern science. It has been proved effectively and can guide Clinical, therefore should be widely applied. |