Based On The Data Mining Of Coronary Heart Disease And Coronary Heart Disease, Diabetes Mellitus Evidence Rule Contrast Research

Objective:To investigate the clinical effects of traditional Chinese medicine (TCM) treatment of coronary heart disease (CHD) with diabetes mellitus (DM) with the systematic evaluation method.Based on large database, by collection of hospitalized patients with coronary heart disease (CHD) as the first diagnosis, to compare the TCM syndrome elements, symptoms, and the use of Chinese medicine between the simple CHD (SCHD) and CHD with diabetes mellitus (CDH-DM), and try to explore the relationship between TCM syndrome elements and physical-chemical indexes.Research Methods:Using RevMan5.1.6statistical software in the system evaluation section.Using SQL Server2008to merge the original database, through further extraction and cleanup, then form the target database. Using Clementine software for data mining.Results:The result of system evaluation shows that in the treatment of CHD with DM, TCM is superior to pure western medicine treatment in the improvement of clinical symptoms and electrocardiogram. It also induces less adverse reactions at the same time.This study suggests that patients of SCHD and CHD-MD are mainly over55years old. In the patients less than55years old, the conditional probability of the male is2times that of the female, while for the patients more than70years old, the conditional probability of the female patients is1.8times that of the male. The distributions of CHD-DM in gendre and age are almost the same with those of SCHD.The common symptoms of SCHD are chest tightness, chest pain, shortness of breath, fatigue, palpitations, and dizziness. While for the CHD-DM, the incedences of fatigue, sweating, dry mouth, constipation, tinnitus, deafness, vertigo, leg edema, limb numbness, cold stomach, and oliguria are higher than SCHD. Dark purple tongue and ecchymosis phenomenon in the SCHD patients are more common than the CHD-DM patients, and less fluid and cracking tongue in the CHD-DM patients are more prominent. The string-like pulse, thready pulse, regulrly intermittent pulse are more common in the SCDH patients, while the slippery pulse, sunken pulse, rapid pulse, weak pulse, slow pulse are more prominent in CHD-DM patients.The syndrome elements of CHD are mainly in heart for disease location, Yang deficiency of disease characteristics. For the CHD-MD patients, the syndrome elements of disease locations in liver and kidney, and disease characteristics of Qi deficiency, Yin deficiency, and blood deficiency, are higher than those in the SCHD patients. Whether with DM or not, the syndrome types of CHD present as liver and kidney’s Yin deficiency (blood deficiency), heart Yang deficiency, phlegm obstructing lung, Qi and Yin deficiency, spleen and stomach deficiency, Qi stagnation, and blood stasis.The blood-activating and stasis-removing drugs are most frequently used in CHD patients, such as Taoren, Honghua, Danshen, Chuanxiong, and etc. Spleen-strengthening and phlegm reducing drugs are paid more attention to be used in CHD-DM patients on the basis of activating blood and removing stasis, such as Fuling, Banxia. The pairs of Taoren-Honghua, Gualou-Xiebai, Maidong-Wuweizi, Danggui-Dihuang are the most frequently used in SCHD patients. The pairs of Taoren-Honghua, Chenpi-Banxia, Maidong-Wuweizi, Gualou-Xiebai are the most frequently used in CHD-DM patients.Suffocation, expectoration, chest pain, chest tightness, dizziness, white fur, and fatigue are more important to predict the symptom of phlegm; fatigue, shortness of breath, palpitations, wheezing, dizziness, sweating, leg edema, poor appetite, chills, frequent urination, tinnitus, deafness, and abdominal distension are more important to predict the symptom of Qi-deficiency; chest pain, constipation, poor sleep, dry mouth, rib-side distention, leg edema, heartburn, chest tightness, headache, suffocation, and bad breath are more important to predict the symptom of blood stasis; deafness, dim eyesight, dizziness, palpitations, constipation, shortness of breath, cold extremities, chills, limb numbness, thick tongue coating, poor sleep, and thin tongue coating are more important to predict the symptom of blood deficiency:chest tightness, suffocation, chest pain, palpitations, leg edema, stomach swelling, and oliguria are more important to predict the symptom of Yang deficiency.The study found that the syndrome elements are the same for CHD with the different number of coronary lesion branches. Yang deficiency are the most common one, blood stasis and phlegm turbidity are the secondary ones. The left ventricular ejection fraction of phlegm and Yin deficiency patients are the lowest. The C-reactive protein (CRP) level in Yin deficiency and Qi deficiency patients is relatively high. The average level of LDL-C in Qi stagnation CHD-DM patients is higher than in SCHD patients. However, due to the severe lack of physical-chemical examination data, we haven’t found a suitable data mining method to explore the relationship between syndrome element and the physical-chemical indexes. Further research is needed in this field.Conclusion:System evaluation indicates that TCM treatment of CHD with DM has better curative effect in the clinical symptoms and electrocardiogram improvement.The differences and correlations between the regulation of syndrome-treatment of SCHD and CHD with DM have been studied with various data mining methods. Meaningful results have been achieved in the syndrome elements distribution and decision method.