| Obesity means an over-deposition or odd redistribution of body fat results from a caloric intake exceeding caloric consumption. Meanwhile the body weight increases significantly. With the development of living standard and the alteration of material conditions, the morbidity of obesity has increased in China. The mechanism of obesity in ancient medical science of China mainly lies in two aspects of deficiency in origin and enrichment in symptom. The former mainly refers to Qi-Deficiency caused by spleen weakness while the latter basically stems from phlegm. Now it can be observed clinically that the advantage of acupuncture weight control relies heavily on its bidirectional regulation and acupuncture therapy can help people lose weight by means of integration as well as regulation function of the meridian and acupoint.ObjectiveAnimal experiment:The obese model of80SD rats were induced by using high fat feed. The successful ones were used in the study and received therapy of moxibustion and electroacupuncture, and acupoints of fat3-needle (Daimai(double), Zhongwan, Zusanli(double)), Guanyuan were used during the therapy. We observed the effect of weight loss by blood lipid, serum from visceral fat, SOD, MDA, NO, leptin levels, interscapular brown fat. We explored the effect of the fat3-needle therapy for simple obesity and wondered whether there is a internal connection between the index and the mechanism of the moxibustion and electroacupuncture of the researchClinical trial:obese subjects were randomly grouped, acupoints of fat3-needle were selected as the main acupoints.Different treatments were applied to patient and different assistant acupoints were chosen according to their TCM syndrome:three methods by which acupuncture plus auricular point group, moxibustion plus auricular point group, simple group, auricular point therapy with TCM syndrome of patients with simple obesity, through the comparison of different methods of body mass index before and after treatment in patients with (BMI) and waist to hip ratio (WHR), the changes of blood lipid, blood glucose, to explore the clinical efficacy of different acupuncture methods of weight loss, summarizes the suitable scheme of treatment of simple obese patients.MethodAnimal experiment:a randomized control method to molding good rats were divided into3group, model group, moxibustion group, acupuncture group, given different treatment methods respectively, body weight, body length, Lee’s index, visceral fat, blood lipid, serum SOD, MDA, NO, leptin levels, interscapular brown fat index.Clinical trial:Patient participated in the observation were diagnosed as simple obesity and were selected in the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Department of acupuncture and moxibustion. body weight index above BMI>24.0, divided into acupuncture plus auricular point sticking group, group simple Moxibustion plus auricular point group, auricular point. Jin’s three-needle acupuncture point selection using the Fat3-needle (Daimai(double), Zhongwan, Zusanli (double)) and abdominal umbilical week8points (Tianshu (double), huaroumen (double), Wai Ling (double), Xia Wan, Shimen), Guan yuan; auricular point using the triple energizer, endocrine, subcortical, sympathetic, spleen, stomach and so on. Each treatment time of30min, every other day for1times,10times to1course of treatment, continuous treatment of2courses,3days rest between treatments. Female menstruation to stop treatment. Auricular replaced2times a week,3-4days to replace1times, treatment time. The needle. All patients were given proper guidance of life. Evaluation standard of curative effect was studied by the1998China Health Science and Technology Institute of obesity will be the fourth revision of the standard.ResultsAnimal experiment:1. Dfferences of moxibustion and electroacupuncture on reducing the rat perirenal fat weight, pericardial fat weight genital fat (fat epididymal/ovary) were statistically significant. And they indicated that the method of moxibustion and electroacupuncture were shown to be able to reduce the effect of visceral fat, and the curative effect is definite.2. moxibustion and electroacupuncture could reduce the serum total cholesterol (P<0.01), triglyceride (P<0.01), LDL-C (P<0.01), HDL-C (P<0.05), can be increased by Acupuncture and moxibustion group, no significant difference between the two groups of rats index (P>0.05), indicating that a considerable effect of these two kinds of treatment methods acupuncture and moxibustion.3. moxibustion can increase the serum of SOD rats (P<0.05), the activity of hypothalamic leptin (P<0.01), and decrease the level of MDA (P<0.01), the differences were statistically significant; electroacupuncture treatment method can increase the serum SOD activity (P<0.01) and the hypothalamic leptin (P<0.01), reduced MDA level (P<0.01) and the content of NO in serum (P<0.01), the difference was statistically significant. Through the acupuncture and moxibustion group, two groups had no statistically significance of serum SOD, MDA, NO, leptin level difference (P>0.05), indicating that a considerable effect of these two kinds of methods of treatment of acupuncture and moxibustion.4. under the electron microscope observation, acupuncture group and moxibustion group of obese rat brown adipose tissue morphology tended to be normal state. We can infer the electroacupuncture and moxibustion heat production system can stimulate fat in the body, increase energy consumption, to achieve weight loss effect.Clinical trials:1. Electroacupuncture and auricular point group and Moxibustion plus auricular point group before and after each course of treatment were compared, a lower body mass index, waist hip ratio were significant, but simple auricular point group before and after treatment were compared, body mass index, waist hip ratio reduction had no statistical significance. The two methods in the treatment of acupuncture and moxibustion to reduce the body mass index, waist hip ratio is effective, simple auricular-plaster therapy cannot reduce the weight index.2. Moxibustion and electroacupuncture in regulating blood lipid, especially has obvious advantages, triglyceride, high density lipoprotein and so on, but the difference between them was no significant effect of the. In the aspect of reducing blood sugar index, differences in efficacy of moxibustion and electroacupuncture has no statistical significance.Conclusion1. Fat3-needle therapy for treatment of simple obesity clear curative effect;2. Acupuncture and moxibustion in2weight loss results are satisfactory, because moxibustion is a kind of easy to master the basic operation skill, if operating properly, patients can be treated at home with the assistance of their family, and they are more convenient for clinical use;3. The two methods in the treatment of acupuncture and moxibustion can reduce the body mass index, waist hip ratio of patients, and the younger patients lose weight effect is more significant;4. In the animal experiment, the therapies of moxibustion and electroacupuncture were all effective in reducing serum total cholesterol, triglyceride, LDL-C (P<0.01), increasing HDL-C. In addition, they can increase the serum SOD activity and the hypothalamic leptin, reduce MDA level and the content of NO in serum. However, electroacupuncture seemed to be more effective in increasing the serum of SOD rats and in reducing the content of NO in serum;5. During the clinical trial, moxibustion and electroacupuncture can decrease the BMI and WHR, both of the therapies can also lower the triglyceride and increase HDL to regulate blood lipids, and the effect is clear. In the observation we can find that moxibustion tends to lower blood sugar levels as well.6. Ear pressure in acupuncture weight loss can be used as an auxiliary means in concert with moxibustion and electroacupuncture, if only a simple ear pressure, effect of the more limited. |
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