| Purpose:For the best play the role of Chinese medicine in the treatment of rheumatic diseases, under a systematic review of ancient physicians etiology of rheumatoid arthritis pathogenesis related literatures and differential treatment, to collect and investigate the treatment of rheumatoid arthritis academic treating thoughts and experiences of mentor Professor Wang Yue, then systematically collated and summarized the laws of TCM Treatment of rheumatoid arthritis.Method:Part 1. Literature Study:The collection of ancient literature, modern (nearly 15 years) medical books, journals, papers, monographs and other clinical medical research literature, on the rheumatoid arthritis, then working to systematically organize, analyze, summarize, So to analyze the ancient physicians class rheumatoid arthritis disease name, pathogenesis, therapy and prescription drugs, such as profiles, noted that the current TCM Syndrome, then study the existing problems of rheumatoid arthritis, and discuss future direction of development.Results:1.Wide range of clinical treatment methods, and the lack of uniform standards syndrome type and efficacy criteria, the lack of depth in a prospective comparative study, the treatment effect is poor repeatability, low reliability, short of objective assessment and comparability;2.Study mainly on clinical efficacy, multi-sample small number of cases observed, besides the short-term clinical efficacy, lack of long-term efficacy of tracking follow-up. Clinical efficacy and safety is not guaranteed, nor beneath conclusions convincing; TCM syndrome effect relationship and dose-response was observed.3.Treatment of rheumatoid arthritis is not deepening. Drug mechanism of action, side effects, strengthening the scientific and theoretical basis, and reliability need to determine.Conclusion:In recent years physicians are tirelessly research, and explore in the rheumatoid arthritis that has made certain achievements, promote the improvement of clinical efficacy, and knowledge of the etiology and pathogenesis of Chinese medicine has been deepen, therapeutic role and increasingly prominent. But there are still some drawbacks and shortcomings that required comprehensive use of various treating method, in accordance to the patient’s body, living environment, and rest rules, severity, and length of illness, efforts to develop a more comprehensive individualized treatment programs to control disease progression and improve quality of life for patients.Part 2. Clinical studies:Mentor Professor Wang Yue’s diagnosis and treatment on 190 cases of rheumatoid arthritis patients with clinical data are collected. The clinical manifestations and specific medication patients were classified and using Microsoft Office-Excel software for statistical analysis with TCM syndromes, therapy, medication and other relevant data. Academic thought and clinical experience, clinical characteristics and medication are summarized in according to mentor Professor Wang Yue Treating rheumatoid arthritis, rules of TCM Treatment of rheumatoid arthritis.Result:In the 190 cases study, more number of female patient than male’s, and it’s ratio on 4.27:1; predilection for ages 40-59 years old; As for syndrome type; the highest frequency of mixed cold and heat syndrome (55.79%), followed by mixed wind-cold and dampness (27.89%), deficiency of genuine qi and with pathogenic factor (11.05%), rheumatic fever (3.68%) and sputum obstruct syndrome (1.58%). up to 2696 cycles on a total of 126 kinds of TCM frequent used,; the top five herbs are rheumatism medicine, tonic, diaphoretic, antipyretic, blood circulation and other drugs; the herbs are guizhi ramuleus cinnamon, paeonia lactiflora pall. Soposhnikovia divaricata schischk, glycyrrhiza yralensis fisch, sinomenium acuturn.Conclusion:The study shows that Professor Wang Yue drugs employed by warm-based medicine, compatibility cold medications. Reflects the clinical use of drugs in cold/warm mixed characteristics.bitter vent warm dry, combined with sweet ease up, supplemented pungent vent circulation. Making the match with three herbs to have a bitter venting, pungent sweet divergence, motivatiion and guard, also loose and discharging, those are expelling irregular to protect the positive strength. Meridian herbs related to the Gan, Shen, Pi, are important factor inherent in the disease.In the treatment of this disease, Professor Wang Yue employed commonly four methods, that’s advocated sweat, warm, clear, tonic, or blend together for the whole course. The early stages, advocates with sparse external and sweating method; pathogenesis of the warm method, while serious symptom will apply clear & eliminate method; chronic illness would emphasize supplement therapy. Acute disease with onset of pain in the initial stage must be treated the symptoms, mainly focusing expel ailment and improve of circulation of meridian, used with herbal branch, vine, worm, insect types.chronic illness on joint swelling deformation required treatment of expelling sputum phlegm and stasis. |