Studies On The Chemical Constituents Of Two Medicinal Used Orchidaceous Plants: Pleione Yunnanensis And Dendrobium Devonianum

This paper reported the systematically phytochemical investigation on two valuable medicinal used orchidaceous plants:Pleione yunnanensis and Dendrobium devonianum.By using chromatography techniques,42 compounds were isolated from the EtOH extracts of the tubers of Pleione yunnanensis. On the basis of chemical methods and spectroscopic techniques, the structures of 39 compounds were elucidated, including 27 stilbenoid derivatives,4 glucosyloxybenzyl 2-isobutylmalates,2 sterols and 6 other compounds. Among these compounds,12 compounds were new ones; 13 compounds were isolated from genus Pleione for the first time; 2 compounds were isolated from the family of orchidaceae for the first time; all the compounds were isolated from this plant for the first time. New compounds were named as shancigusins A—I (1—7 and 35—36) and Pleionols A—C (8—10), sequencely. The known compounds were identified as follows: 3’-O-methylbatatasinⅢ(11), batatasinⅢ(12), batatasinⅢ-3-O-β-D-glucopyranoside (13),3’-O-methylbatatasinⅢ-3-O-β-D-glucopyranoside (14), 3,3’-dihydroxy-2,6-bis(4-hydroxybenzyl)-5-methoxybibenzyl (15), shanciguol (16), IsoarundininⅡ(17), IsoarundininⅠ(18), Arundinin (19),2,7-dihydroxy-4-methoxy-9,10-dihydrophenanthrene (20),4,7-dihydroxy-2-methoxy-9,10-dihydrophenanthrene (21), shancidin (22),2,7-dihydroxy-1-(p-hydroxybenzyl)-4-methoxy-9,10-dihydrophenanthrene (23),2,7-dihydroxy-l-(p-hydroxybenzyl)-4-methoxyphenanthrene (24), Blestriarene C (25), shanciol H (26), shanciol F (27), p-sitosterol (28), daucosterol (29),1-Monoarachidin (30),1-Octacosanol (31), Succinic acid (32), adenosine (33), (-)-syringaresinol (34), militarine (37), Dactylorhin A (38) and Coelovirin A (39).Kinds of chromatographic methods were employed to isolate and purify compounds from Dendrobium devonianum. As a result,52 compounds were isolated and 39 compounds were identified using spectroscopic techniques, including 12 stilbenoid derivatives,9 amides,5 acids,2 sterols,1 flavanone and 10 other compounds.. Among these compounds,2 were new compounds named Dendrodevonins A and B (1—2),5 were isolated from genus Dendrobium for the first time,9 were isolated from family of orchidaceae for the first time; all the compounds were isolated from Dendrobium devonianum for the first time. The known compounds were identified as follows: 3-hydroxy-4’,5-dimethoxybibenzyl (3), gigantol (4),3,4’-dihydroxy-5-methoxybibenzy (5), batatasinⅢ(6), tristin (7),3,4’,5-trihydroxybibenzyl (8),3,3’,5-trihydroxybibenzyl (9), Dendrocandin C (10), moupinamide (11), N-trans-Coumaroyltyramine (12), N-trans-4-Coumaroyldopamine (13), N-trans-caffeoyltyramine (14), p-hydroxyphenylpropionyl tyramine (15), N-cis-Coumaroyltyramine (16), N-trans-Grossamide (17), N-cis-Grossamide (18), Cannabisin G (19), 2,4,7-trihydroxy-9,10-dihydrophenanthrene (20),2,5-dihydroxy-4-methoxy-9,10-dihydrophenanthrene (21),4’,5,7-trihydroxyflavanone (22), dihydroconifery acetate (23), Ethyl 4-hydroxycinnamate (24), cinnamic acid (25),4-hydroxy cinnamic acid (26), 4-hydroxyphenylpropionic acid (27),4-hydroxybenzoic acid (28),3,4-dihydroxybenzoic acid (29), ErigesideⅡ(30), Citrusin C (31), dihydrosyringin (32), Leonuriside A (33), adenosine (34),β-sitosterol (35), daucosterol (36), (+)-syringgaresinol-β-D-glucopyranoside (37), sucrose (38) and 1-Monoheptadecanoin (39).