| he quinolizidine alkaloids in the legume genus Lupinus are reportedly toxic to the grazing livestock in parts of North America. Alkaloids in two species of Texas bluebonnets, Lupinus texensis and Lupinus subcarnosus were isolated and characterized by a combination of thin-layer chromatography and gas chromatography-mass spectrometry. Lupanine, ;Sparteine is reportedly metabolized in mammals by formation of an N-oxide which dehydrates to ;Quantitative analysis of alkaloids in seedlings of various ages and their relative concentrations provided data with biogenetic implications, which were substantiated by biosynthetic studies. Feeding radiolabeled lupanine and... |
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