Study On The Preparation Of One Kind Of Glucose-lowering Royal Jelly Compound

Mainly containing royal jelly with Gen-seng and Ganoderma Lucidum as addition, glucose-lowering lyophilized royal jelly compound (FSL) is one kind of health-care food that has hypoglycemic effects. In the study the best formula of the compound, its hypoglycemic effects and acute toxin were investigated. Experiment on best formula showed that:Gen-seng can be best distilled when being put in 70% alcohol (5 times of Gen-seng) distilling for 4 times (45min per time) . Ganoderma Lucidum can be best distilled when being put in distilled water(15 times of Gen-seng) distilling for 3 times(1hour per time) at 100℃. Preparing experiments showed that royal jelly at dosage 1. 5g/kg, 2. 4g/kg, Gen-seng at dosage 0. 15g/kg, 0. 35g/kg, Ganoderma Lucidum at dosage 0. 09g/kg, 0. 24g/kg were most effective in lowering glucose respectively. So these dosage were fit for the next selection experiment. Before lyophilization, adding distilled water (the same volume of the mixture) in mixture of royal jelly, Gen-seng and Ganoderma Lucidum, then pretreating them, we can get high-quality preparation-FLS, which had abundant nutritious ingredient admitted by relevant authority.Primary study on FLS' s hypoglycemic effects showed that: the effective glucose-lowering range of FLS was from 300mg/kg to 1000mg/kg. It had no significant effects on blood glucose of normal mice treated with high(800mg/kg), moderate (500mg/kg), low(300mg/kg) dosage of FLS once in lday or 10 suceesive days respectively. 14-suceesive days administration of FLS (high, moderate, low dosage) had no significant effects on liver glycogen of normal mice while it can significantly improve their glucose tolerance...