An Environmentally Benign Procedure For The Synthesis Of Aryl And Arylvinyl Nitriles Assisted By Microwave In Ionic Liquid

This thesis focuses on the study of cyanation reactions with potassium hexacyanoferrate(II) catalyzed by palladium in ionic liquid under microwave irradiation. The ionic liquid containing catalyst system can be recycled. It involves two parts:Part 1: We focus on the review of palladium-catalyzed cyanation reaction in recent years, recent development of microwave in organic synthesis and application of ionic liquid in organic reactions.Part 2: We focus on the application of cyanation reaction in ionic liquid ([BMIm][BF₄]). We use microwave instead of the traditional heating and reaction time is obviously reduced, most of them give high yields. After extraction with ethyl actate/petroleum ether to separate the products from the catalyst system, the resulting ionic liquid was pumped for several minutes and reused for the next reaction directly. The resulting [BMIm][BF₄] containing the Pd-catalyst can be reused successfully five times without reduction of its catalytic activity. The "green" solvent is realizing harmless, economical and environmentally friendly.In this thesis, we report the cyanation reactions of various aryl bromides and arylvinyl bromides with K₄[Fe(CN)₆]. All the compounds are identified by ¹H NMR, ¹³C NMR and MS.