Applications Of Ionic Liquid As Catalyst And Green Medium In Organic Synthesis.

Green Chemistry is already to become one of the international chemistry research front edge nowadays. In this article, our research includes two parts: One is about the ionic liquid, as a new type green reaction medium as well as catalyst, which possess super-ordinary physical chemistry property and easy to be modified the structure of anions and cations. Ionic liquids were considered the replacement of the commonly used volatile organic solvent. Recently, ionic liquids as a kind of green solvent and catalyst even as a carrier for catalyst have drawn much attention due to the important roles they played in organic reaction. The other part concern about the polymer supported catalyst which employed as a new type green catalyst. This article introduces the following researchers:1. The Knoevenagel condensation reaction of series of aromatic aldehydes with active methylene compounds was catalyzed by functionalized ionic liquid in water to afford the desired products in good yields. The reaction condition is mild, the procedure and work-up is simple.2. The Knoevenagel condensations reaction of series of aromatic aldehydes with active methylene compounds in the absence of solvent has been found to proceed with high yields under grinding conditions. The reaction condition is mild, the procedure and work-up is simple.3. The Knoevenagel condensation reaction and Micheal addtion reaction of series of aromatic aldehydes with active methylene compounds was catalyzed by ethylenediaminetetraacetic acid tetrasodium salt in ionic liquid/water medium to afford the desired products in good yields. The reaction condition is mild, the procedure and work-up is simple. Ionic liquid is able to be recycled.4. The high polymer supported catalyst was used to synthesis of bi(indolyl)methanes, namely, the nucleopillic replace reaction of heterocyclic compound indole and aromatic aldehyde indichlomethane.