Research And Optimization Of Filtration Features Of VB₁₂ Fermentation Broth

The filtration of VB₁₂ fermentation broth is an important operation in medicine production, it has a direct effect on quality and produce efficiency. The way of direct filtration can't reach industrial needs. In the case of not changing the quondam filtration equipment (plate filter), the fermentation broth has to be pretreated by flocculation. The structure of filter cake is improved by adding diatomaceous earth and the main factor effecting filter rate is researched.Firstly, by doing the orthogonal tests, the main influence factors that influenced the flocculation are studyed. The results show the best conditions: polyaluminum chloride flocculant, 7% addition, pH=7, with the stirring speed of 1.26m/s, stirring 45s. By pressure filtration experiment, filter feature after flocculation could be obtained. The influence of the filter cake structure and the filter rate are discussed by adding diatomaceous earth. Special resistance and compressibility were researched. The results show that the filter cake after flocculation is high compressible, the special resistance after adding diatomaceous earth decreases, compressibility coefficient decreases to 0.387, and the filter rate is improved by 30% when the addition is 3%.In this paper, the configuration character is observed by electron microscope, the results show: configuration character affects the structure of filter cake and filter process greatly. The granule floccule can improved the structure of filter cake and the filter rate better than the filar floccule.