Imaging Features And Risk Factors Of Resting Cerebral Infarction In Patients With Cerebral Infarction

Objective:To study the image character and risk factor analysis of silent brain infarction in patients with ischemic stroke, and find out the mechanism and etiology of SBI.Methods:A total of196consecutive patients with acute ischemic stroke that underwent brain MRI were enrolled in this study. The prevalences of vascular risk factors and periventricular white-matter changes in a SBI-positive (n=88) and in a SBI-negative group (n=108) were compared. The characteristics of SBI in image and the prevalences were further evaluated with respect to stroke subtype.Results:The frequency of SBI among the196study subjects was44.9%, and59.1%of the study subjects had single-SBI lesions,40.9%of the study subjects had multiple-SBI lesions. The most common lesion site was basal ganglia (72.2%). The results of risk factors compared between2groups showed that age, hypertension and the presence of PWMH lesion were significantly associated with SBI.(P<0.05). The frequency of SBI was higher among those with the small-vessel disease type (61.7%) than in those with the large-artery disease (40.0%)(P<0.05).Conclusion:The prevalence of SBI in patients with ischemic stroke was found to be high, and hypertension and a diffuse white-matter lesion were found to be the most important risk factors of SBI. Small-vessel disease was found to be closely associated with SBI.