Analysis Of Chinese Herbal Medicine With Acute Postprandial Hyperplasia

OBJECTIVE:By observing and following up 112 AIDS patients with hyperlipidemia induced by HAART, the symptoms and syndromes of patients were studied, in order to provide reference for the clinical treatment of hyperlipidemia induced by HAART.METHODS:112 AIDS patients with hyperlipidemia induced by HAART were collected. Clinical epidemiological cross-sectional survey method was adopted, the AIDS TCM Syndrome four diagnostic information collection form prepared by AIDS Research Center of China Academy of Traditional Chinese Medicine was adopted to collect clinical symptoms. Patients who visited Ditan Hospital of The Affiliated Hospital of Capital Medical University and met the diagnostic criteria were collected as research subjects, the completed medical records were input into EXCEL form, SPSS 20.0 was adopted for statistical analysis. Through factor analysis, non-parametric test, rank sum test and correlation test, the paper made statistical difference analysis on the symptoms and syndromes of patients with hyperlipidemia induced by HAART.RESULTS:1.The Symptom Characteristics of 112 AIDS Patients with Hyperlipidemia induced by HAARTThe main symptoms of patients are fatigue, loss of appetite, sleepy body and heavy weight, abdominal distension, amnesia, aching pain in the loins and knees; tongue nature is scalloped tongue, pale tongue and light-reddish tongue; tongue has white fur, thin fur, greasy fur; pulse condition is fine pulse and slippery pulse.2.112 The Syndrome Characteristics of 112 AIDS Patients with Hyperlipidemia induced by HAART According to factor analysis, the main syndromes consist of spleen-deficiency and phlegm-stagnation and phlegm blood stasis, and are mainly spleen insufficiency caused by spleen-deficiency and phlegm-stagnation.3.112 Different Symptoms and Syndromes of 112 AIDS Patients with Hyperlipidemia induced by HAART3.1 Comparison of Symptoms of Patients with Different Genders The symptoms of male patients mainly consist of white fur, fatigue and thin fur; the symptoms of male patients mainly consist of fatigue, white fur, loss of appetite, etc. The symptoms of male patients showed differences in soreness and weakness of waist and knees, which indicate deficiency of the liver and kidney; female patients have differences in insomnia, amnesia indicates deficiency of the liver and kidney, insomnia indicates deficiency of yin and fire excess.Patients with different genders have differences (P＜0.05) in thin fur, scalloped tongue, thready pulse and other symptoms.3.2 Comparison of Symptoms of Patients at Different Ages The main symptoms of patients aged 20 to 39 years old contain white fur, fatigue and thin fur; the main symptoms of patients aged 40 to 69 years old consist fatigue, white fur, sleepy body and heavy weight and other symptoms. Patients aged 20 to 39 years and patients aged 40 to 69 years all have soreness and weakness of waist and knees and amnesia, patient at different ages have deficiency of the liver and kidney, indicating that HIV virus can easily lead to deficiency of the liver and kidney. Patients at different ages have differences (P＜0.05) in limb numbness, chest pain, greasy fur and other symptoms.3.3 Comparison of Symptoms Under Different Infection PathsThe main symptoms of patients infected through sexual contact consist of white fur, fatigue, thin fur. The main symptoms of patients infected through blood transfusion consist of fatigue, amnesia, sleepy body and heavy weight. Patients infected through sexual contact have differences in the degree of soreness and weakness of waist and knees, this may be caused by sexual strain and kidney essence depletion, which lead to deficiency of the liver and kidney, as well as soreness and weakness of waist and knees. Patients infected through blood transfusion have difference in insomnia, according to Chinese medicine, blood belongs to yin, the lack of blood causes deficiency of yin; AIDS blood directly leads to deficiency of yin. Patients infected through different paths have differences (P＜0.05) in white fur, thin fur, scalloped tongue and other symptoms.3.4 Comparison of Symptoms of Patients at Different PeriodsThe main symptoms of patients at asymptomatic period consist of white fur, loss of appetite, thready pulse and so on; the main symptoms of AIDS patients consist of white fur, fatigue, thin fur and so on. Patients at asymptomatic period and AIDS exhibit similar syndromes at different ages, it is concluded that HIV-infected patients at different stages have deficiency of the liver and kidney and syndrome rule.Patients at different periods have differences (P＜0.05) in white fur, fatigue, thin fur and other symptoms.3.5 Comparison of Syndromes of Patients With Different GendersRegardless of gender, the syndromes of male and female patients are mainly spleen-deficiency and phlegm-stagnation syndrome. The proportion of spleen-deficiency and phlegm-stagnation syndrome in women is higher than that of men; the proportion of phlegm blood stasis syndrome in men is higher than that of women. 3.6 Comparison of Syndromes of Patients at Different AgesAmong different age groups, patients of 20-39 age group and 40-69 age group mainly have spleen-deficiency and phlegm-stagnation syndrome, the proportion of spleen-deficiency and phlegm-stagnation syndrome in 20-39 age group is higher than that of 40-69 age group; the proportion of spleen blood stasis syndrome in 40-69 age group is higher than that of 20-39 age group.3.7 Comparison of Syndromes of Patients Infected Through Different PathsAmong patients infected through different paths, the main syndromes of patients infected through sexual contact and blood transfusion are spleen-deficiency and phlegm-stagnation syndrome. The proportion of spleen-deficiency and phlegm-stagnation syndrome in blood transfusion group is higher than that of sexual contact group; the proportion of spleen blood stasis syndrome in sexual contact group is higher than that of blood transfusion group. 3.8 Comparison of Syndromes of Patients at Different PeriodsDuring different periods, the syndromes of patients at asymptomatic period and AIDS period are mainly spleen-deficiency and phlegm-stagnation syndrome. The proportion of spleen-deficiency and phlegm-stagnation syndrome in asymptomatic period group is higher than that of AIDS period group; the proportion of spleen blood stasis syndrome in AIDS period group is higher than that of asymptomatic period group.4.The Treatment Effect and Correlation Analysis of 112 AIDS Patients with Hyperlipidemia induced by HAARTTCM medical interventions have significant effect on post-HAART hyperlipidemia, the applied prescription contains mainly astragalus, rhizoma pinellinae praeparata, dried tangerine or orange peel, poria cocos, white atractylodes rhizome, rhizoma alismatis, hawthorn, root of red-rooted salvia, peach kernel, red flower, angelica sinensis and ligusticum wallichii. TCM symptoms have correlation with laboratory parameters, the symptoms that have positive correlation with TC are:sleepy body and heavy weight, tastelessness, abdominal distension; the symptoms that have positive correlation with TG include:red tongue, scalloped tongue, deep pulse, false pulse; the symptoms that have positive correlation with LDL-C include: sleepy body and heavy weight, heavy head, tastelessness, loss of appetite, abdominal distension, pale tongue and slippery pulse.CONCLUSIONS:1.The main symptom and syndrome of AIDS patients with hyperlipidemia induced by HAART is deficiency, showing an overall trend of intermingled deficiency and excess, the syndrome is mainly Qi deficiency and deficiency in spleen, with phlegm-based syndrome, the main treatment method is tonifying spleen, eliminating phlegm, activating blood and absorbing clots. The main symptom and syndrome of AIDS patients with hyperlipidemia induced by HAART are very similar to those of ordinary AIDS patients and ordinary patients with hyperlipidemia, but with certain differences, this provides reference for clinical diagnosis and treatment.2.The main symptom and syndrome differ due to differences in gender, age group, infection path and ways and period, the clinical treatment should give consideration to gender, age group, infection path and period.3.The applied TCM prescription contains mainly astragalus, rhizoma pinellinae praeparata, dried tangerine or orange peel, poria cocos, white atractylodes rhizome, rhizoma alismatis, hawthorn, root of red-rooted salvia, peach kernel, red flower, angelica sinensis and ligusticum wallichii. After treatment, the blood lipid level is improved. Because of the high efficiency of HAART in the treatment of AIDS, the AIDS mortality is significantly reduced, but the side effects becomes more obvious with the long treatment duration, side effects affect treatment effect and treatment of dependence. The paper studied the treatment of TCM for patients with hyperlipidemia induced by HAART, the blood lipid level was reduced, and there was no side effect of statin drugs. This indicates the advantages of traditional Chinese medicine, it provides a new treatment option for patients with hyperlipidemia induced by HAART.4.The TCM symptoms have correlation with laboratory parameters, such as TC, TG and LDL-C. It is inevitably to encounter patients who meet these clinical indicators but have symptoms, it can draw reference from western medicine test indicators and adopt traditional Chinese medicine for treatment, and provide better clinical services.