A Preliminary Quantitative Study On The Clinical Efficacy Of TCM Syndrome And Syndrome Differentiation

Objective:①To understand the clinical distribution of the common syndromes of XiaoKe.②To observe and compare the efficacy and safety of modified Baihu Jia Cangzhu decoction in treating Type2Diabetes Mellitus with Middle-energizer Damp-heat Syndrome.③To find out the feasibility of objective syndrome differentiation and Curative effect evaluation through quantifying information of TCM four diagnosis method for XiaoKe.Methods:Clinical survey:①Method. randomly selected150inpatient’s medical records.②Data Collection:height, age, gender, BMI, hospital stays,duration, TCM and western medicine diagnosis during admission, four diagnostic information of the first3days after admission.③Data analysis: SPSS17.0software.Clinical trials①Method. Treatment group:30outpatients and inpatients from affiliated hospital of Chengdu University of TCM who meet the standards, treated with metformin hydrochloride combined baihu jia cangzhu decoction;Control group:30cases from ChengDu Guanghua health service centers(CHSC) and meet the standards,with metformin hydrochloride;Foundation treatment of the two groups (the same diet, exercise, healthy knowledge education, etc.);Take4weeks as treatment cycle.②Observations:Four examinations information of TCM (record before and after treatment) FPG,2HPG (3days after the start and before the end of treament);HbA1C, TC, TG (the last results before and after experiment)and whether or not appears adverse reactions.③Data analysis:SPSS17.0Results:①Middle-energizer Damp-heat Syndrome was common in every stage of XiaoKe;②The total effect and TCM symptoms curative effect, FPG,2hPG,HbA1C of treatment group is better than control group (P<0.05);Before and after treatment the score of treatment group about thirst with a desire to drink, profuse sweating, vexation and heat intolerance, abdominal fullness, feeling of heaviness in the head and body, tongue manifestation, FPG、2hPG、HbA1C were decreased and had statistical significance.Conclusion:Research proved that It was feasible that using statistical methods to study TCM objectively and quantitatively; Baihu Jia Cangzhu decoction combined with metformin hydrochloride was superior than the use of metformin hydrochloride only in reducing serum sugar, lipid, curing TCM manifestation, also, it was safe, and without adverse reaction. Results suggest that clearing heat to purge fire, dry dampness to fortify the spleen helped controlled the unmanageable blood sugar of the patients with syndrome of flourishing fire-heat and damp-heat encumbering the spleen. Syndrome of diseases is dynamic, affected by many factors such as climate, conditions, course of diseases, as so, don’t be restrained by western medicine logic when studying TCM.