Study On Correlative Factors Of Diabetic Nephropathy And Distribution Of TCM Syndromes

Purpose：Collecting medical records of patients in hospital with type2diabetes anddiabetic nephropathy, and retrospectively analyse it to study therelevantfactors and the distribution of syndromes，so we can reasonablely, accurateand comprehensively understand the clinical medicine status and easy-relatedfactors of diabetic nephropathy,and we can guide the prevention and Chinesemedicine therapy of diabetic nephropathy。Material and method：Explore the correlation between diabetic nephropathy(DN) and related factorsand the distribution of syndromes，to provide ideas to prevent and treat thediabetic nephropathy in the future, this study collected Hospital medicalrecords of hospitalized diabetic patients from January2013to January2014inEndocrinology of Affiliated Hospital in Liaoning University of TraditionalChinese Medicine.270cases with complete data will be grouped into NDN groupand DN group, and count the duration, age, sex, blood lipids, blood pressure,glycated hemoglobin, and other related statistical of the two groups of patients,to explore the correlation between them;Meanwhile, according to itssyndromes,analysis the distribution of TCM。Results：（1） Gender, age, BMI and the incidence of DN no significant (P>0.05).（2） The duration of the occurrence of DN has a very significant difference(P<0.01), positively correlated with urinary albumin was (r=0.153, P<0.05).（3） The occurrence of glycated hemoglobin and DN has significant difference(P<0.05), with no correlation between urinary albumin; fasting glucose and theoccurrence of DN has a very significant difference (P<0.01), and urinary albumin There was a positive correlation (r=0.152, P<0.05); postprandial glucose andno significant incidence of DN (P>0.05).（4） The occurrence of systolic and DN significant difference (P<0.05), andurinary albumin were positively correlated (r=0.134, P<0.05); pulse pressureand the incidence of DN has a very significant difference (P<0.01), albumin waspositively correlated with urine (r=0.193, P<0.01); diastolic blood pressureand the incidence of DN was not statistically significant (P>0.05).（5） High-density lipoprotein cholesterol, total cholesterol, low-densitylipoprotein cholesterol and the incidence of DN was no significant (P>0.05);triglycerides and DN occurs with a very significant difference (P<0.01), andurinary albumin was positively correlated (r=0.276, P<0.01).(6) The occurrence of DN urea nitrogen and highly significant difference (P<0.01), with no correlation between urinary albumin; urine creatinine occurredwith DN no significant (P>0.05).(7) Duration, glycosylated hemoglobin, pulse pressure, triglycerides, bloodurea nitrogen is a risk factor for diabetic nephropathy.(8) NDN group of syndromes in each heat Spleen Up (94cases), accounting for54.34%of the total NDN, followed by Qi and Yin and blood stasis (68cases),accounting for39.31%, liver and kidney deficiency syndrome8cases, accountingfor4.62%, deficiency of both yin and yang minimum (three cases), accountingfor1.73%; DN group up to the liver and kidney deficiency syndrome (43cases),accounting for44.33%, followed by qi and Yin and blood stasis (40cases),accounting for41.24%, deficiency of both yin and yang at least (14cases),accounting for17.53%.Conclusions：(1) Duration, fasting blood glucose, glycosylated hemoglobin, systolic bloodpressure, pulse pressure, triglycerides, blood urea nitrogen and on theincidence of diabetic nephropathy, including duration, glycated hemoglobin,pulse pressure, triglycerides, blood urea nitrogen is a danger of diabetic nephropathy factor.(2) Fasting plasma glucose, systolic blood pressure, pulse pressure,triglycerides the longer the higher the duration, the more severe diabetic kidneydisease.(3) Gender, age, BMI, diastolic blood pressure,2h postprandial blood glucose,cholesterol, high density lipoprotein cholesterol, low-density lipoproteincholesterol, urinary creatinine is not associated with diabetic nephropathy.(4) Diabetes syndromes, damp Spleen most, followed by Qi and Yin and blood stasis,fewer liver and kidney yin deficiency of both card and. Yin Deficiency diabeticnephropathy and liver and kidney and blood stasis syndrome most, both yin andyang deficiency also increased. Diabetes process into diabetic nephropathy, dampSpleen, and gradually evolved into Qiyinliangxu stasis, disease course of time,resulting in liver and kidney syndrome, to the late development of the disease,there deficiency of both yin and yang.