Measurements Of Thermal Properties And Blood Perfusion And Simulation Of Temperature Field In Microwave Hyperthermia For Liver Cancer

For clinical application of invasive microwave hyperthermia treatment for liver cancer induced by ultrasound, the method for on-line measuring the thermal conductivity and blood perfusion of the normal and tumor tissue in the liver cancer is studied. The practical instrumentationsystem is developed and used to do the testing measurements and the practical prediction measurements in the inorganic medium (water, glycerol, and glycol), in vitro and in vivo. Through the numeric simulating of the temperature field in the treatment area, the method of constructing 3D conformal efficient therapy field is put forward, which give the technical basis for controlling temperature and designing therapy projects during the microwave thermal coagulation treatment of liver cancer. The tissue conductivity and perfusion are measured simultaneously with invasive heat disturbing method, which uses an ultraminiature thermister(both a heat disturbing source and a temperature sensor element) by working in constant temperature increment. A method of combining computer simulation and experiment measurements is used to monitor the temperature field. Based on determining the thermal coagulating area with single microwave antenna, multi-antenna heating is presented to implement the 3D conformal therapy of the cancer by constructing the efficient treatment area with same shape and size as the actual tumor.