Microwave Cancer Therapy In Human Thermal Field Analysis And Application

As an inner source in heating bio-materials, microwave has advantages of high efficiency, fast temperature rise, uniformed hyperthermia fields and completely necrotic within coagulation zone. It has been a vital therapy in treating human cancer in recent years, and more and more scholars have paid there attention on this technology, with different studies relevant to the microwave hyperthermia therapy have been developed. As one of the studies, the simulation of thermal fields in tissues during the percutaneous microwave coagulation therapy has been studied. The treatment effect can be forecasted through the simulation, which will not only reduce the risk of the operation, but also bring more confidence to the doctor during the operation.In the work, the finite-difference time-domain method is firstly introduced, and then the PMCT probe, which is a monopole antenna, is analyzed in this method. There is a relation between the electric field value and the Specific Absorption Rate (SAR) of tissues, and the thermal field analysis can be carried out by the relation. In this way, some factors that largely infected the thermal distribution are studied, including input power of the probe, radiation time, and thermal conductivity, blood perfusion, and conductivity.Finally, some vitro animal tissue experiments are carried out, and compare the experiment result with the simulation data. According to the comparing result, we can see that the experimental coagulation shape has good match with the simulation result, and the temperature-time curve are also matched well. As a result, the method of simulating thermal field in bio-tissues with FDTD is accurate in some extent, and can provide some backup in treating predication during clinic operation.