| Background:The correct assessment of autonomic nervous function of the heart is essential for the diagnosis and treatment of cardiac diseases. The malfunction of the autonomic nervous system of the heart usually presents as abnormal heart rate variability(HRV). Nowadays, HRV has become an important index in monitoring cardiac diseases. However, whether the location of myocardial perfusion defect is correlated with the HRV still remains controversial.SPECT has been documented to be a relatively accurate method of detecting the location of myocardial disease. The purpose of the present study was to investigate the relationship between the HRV and the myocardial defects of different site detected by using SPECT.Methods:Hoter ECG was examined in 186 petients. The index of HRV were SDNN, SDANN Index, SDNN Index, rMSSD and pNNSO. SPECT was done in 137 patients whom 59 were found to have abnormal myocardial perfusion. The location of the myocardial defects was analysed the HRV of 6 different locations were compared. Fourty-nine patients underwent coronary arteryangiography and comparision was made among patients with stenosis of 3 different coronary branches and the control.Results:(l)The SDNN and pNNSO were decrease in patients with myocardial defects(P<0.01).(2) Myocardial defects of the apex, anterior, posterior, inferior and intermedia walls had similar affects on the HRV, while defects of the lateral wall didn't show much influence on the HRV.(3)The SDNN, SDANN Index, and SDNN Index were all reduced if coronary artery stenosis was present, especially if the anterior desending artery was involved.Cone I us i ons:The dysfunction of autonmic nervous system of the heart is correlated with the location of myocardial defects. Lesions of the apex, anterior, posterior, inferior and intermedia walls have similar influence on the HRV, while that of the lateral wall has minimum. The stenosis of anterior descending coronary artery also affects the HRV significantly. |
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