Factor V Leiden Mutation And Anticardiolipin Antibodies In Young Patients With Ischemic Cerebrovascular Diseases

OBJECTIVE: The Factor V Leiden mutation(FVL mutation) represents the most common genetic risk factor for venous thromboembolism. However,its role in ischemic cerebrovascular diseases(ICVD) is unclear. Prevalence of the FVL mutation varies with different races.Also,the association between anticardiolipin antibodies(aCL) and ICVD remains controversial.The aim of this study was to investigate whether FVL mutation and aCL were risk factors for ICVD in young adults.METHODS: A case-control study was conducted.Case patients were 44 individuals aged