| To find out the longest effective duration of Mydrin - P and Romi eyedrop on cycloplegia, compare the residual accommodation after cycloplegia by Mydrin - P eyedrop, 1 % Atropine past and Romi eyedrop, analye their effect on ame-tropia. To provide some experiment basis for using cycloplegia properly in clinic.Methods75 children(147eyes) were checked , 4 ~ 16 years, male 32, female 43, mean age : 10.12 years. No organic disease. The patients divided into 3 group: A, 1 % Atropine group; B, Romi eyedrop group and C, Mydrin - P group. Before and after administration of these eyedrops, objective refrection was checked in hand -hold auto refrator; subjective refrection was checked in phoropter, and retinoscopy refraction was finished. Phoropter was used to check the accommodation response and the residual accommodation respectively by " pushup" method.Results1. In Romi eyedrop group , the time of maximum cycloplegia was 60 minutes , the patients can read in the next day ; In Mydrin - P group , the timewas 30 minutes , can read next day.2. Average residual accommodation at the maximum cycloplegia: A, 1% Atropine group 2. 0440 # 0. 95484D , B, Romi eyedrop group 2. 2214 # 0. 6952D, C, Mydrin -P group 2.6656 #0.9999D. The residual accommodation in Romi eyedrop and Atropine groups has no significant difference, Independent- samples T Test p > 0. 05. The residual accommodation in Mydrin - P group was stronger than the other two groups , more significant in myopia eyes.3. Three groups residual accommodation have no relationship with age and refrective status.4. The results were same in cycloplegic refraction with objective retinosco-py and subjective phoropter of each groups of A, 1 % Atropine group, B, Romi eyedrop group and C, Mydrin - P group . ( p > 0.05 )5. Diopter difference of three group before and after cycloplegic refraction, was same in hyperopia, which of Romi eyedrop group was smaller less than 0. 25 D compared with 1% Atropine group in myopia.Conclusions1. The time of maximum cycloplegia effective of Romi eyedrop was 60 minutes , of Mydrin - P was 30 minutes.2. The residual accommodation in Romi eyedrop and Atropine groups was almost same , the residual accommodation in Mydrin - P group was stronger than the other two -groups, more significant in myopia eyes.3. There was no significant difference in the refraction change between groups before and after the administration of these 3 kinds eyedrop. They can all fully cycloplegia.4. Romi eyedrop , Mydrin - P eyedrop can be use in the cycloplegic refraction for children in myopia and hyperopia without strabismus and amblyopia. |