| Lung cancer is a serious health problem in public. According to the data of WHO , the morbidity and mortality of cancer has increased approximately 22% in the past decade. And the lung cancer is the major cancer in the amount of incident ( 1. 2million/year) and death(l. 1 million/year) all over the world. Lung cancer is the first leading death of the cancer in the cities of our country. And the morbidity and the mortality have been increasing rapidly. The mortality of lung cancer in women increases year by year . It is shown that most of the cases are non - smoking women , and the women population attributable risk of smoking is about 20%. So the risk factors still are unclear. Many researches have focused on it, but it hasnt been identified. The objective of this research was to explore the effect of pollution in room , passive smoking and other factors on the incident of lung cancer.Materials and MethodsThe cases were newly diagnosed in 18 hospitals of Shenyang formjune,2000 to December ,2002 with an incident, primary lung carcinoma(ICD -9codel62). These eligible non - smoking women cases dwelled in urban district of Shenyang. We selected 618 newly diagnosed cases with primary lung cancer. And the controls were selected by random from general population. They were frequency matched to lung cancer cases on age of 35 -69. The cases were all clinically diagnosed and got the X - ray and CT of chest. 84. 1% of cases has the diagnosis of cytological or pathological section. The controls were selected with random in the general population in urban districts. They were matched with cases on age within two years. Weused the same questionnaire, and two trained interviewers performed these inter-views face - to - face. The interviews were within two weeks after the diagnosis. The questions included the character of demography, the history of passive smoking , the exposed history of cooking fume, the sorts of fuel, the exposed history of coal fume, the history of using " Kang" , the history of previous diseases of lung, the cancer history of related people and the occupational history. The special persons checked up the materials. The eligible data were coded (table 1) , constructed in computers . We used Mental - Hawansel method and multivariate. Logistic regression analysis to estimate the intensity of the association between these factors and the incident of lung cancer and the statistical significance.ResultThe adenocarcinoma was 65% , small - cell cancer 16. 92% , squamous cell 14.03% ,othem3.40%. The relationship between in - comes ,BMI index and the risk of women lung cancer was in table 3. The risk was higher in the people with higher incomes ,the quartile were 1. 2,2. 03 ,2. 86 respectively. The test of trend was of statistical significance. The passive smoking was refer to the nonsmoking women was exposed in smoke in the occupational position and in the family from their parents or other family members. As a whole ,the passive smoking childhood was related with the lung cancer of non - smoking women ,and the OR was 1. 81. After became adults , the OR of passive smoking in occupational positions and in family were 1.11 and 0. 74 respectively. So the results werent of statistical significance.Cooking fume cooking fume referred to whether the subjects could feel the fume when they were cooking. The people in Shenyanguse soybean oil to cook. The exposition to the cooking fume was of great significance, and the OR was 3. 18(95% CI2. 55 ~ 3. 97).Coal fume coal fume referred to the exposition in room and kitchen while cooking or heating. It was associated to the lung cancer significantly, and the OR was 2.56(95% CI1.83 -4.55).Previous diseases of lung These diseases included tuberculosis, chronic bronchitis, asthma, pneumonia, emphysema etc. They were strongly associated with the lung cancer, and the OR was 1. 80(95%CI1.43 -2.27). The association withthe history of tuberculosis was increased, the OR was 1. 63(95% CI1.46 ~3. 00) The family history of cancer These include... |
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