Evaluation Of Left Ventricular Global Function And Regional Function In Ischemic Myocardium With Tissue Doppler Imaging And Angiography Of Coronary Artery

Objective: To evaluate the clinical value of Tissue doppler imaging(TDI) in quantitative detection of regional and global of left ventricular systolic and diastolic function in patients with coronary artery disease .Methods: Random examination was performed on 81 in hospital. By angiography of coronary artery, we confirm 45 patients(CAD) and 36 control subjests. Tissue Doppler imaging (TDI) is an ultrasonic technique that can be applied to analyse myocardial motion objectively and quantitatively. With pulsed-wave TDI myocardial motion velocity can be measured directly. In this, study ,we also analyse mitral annular velocity in systolic and diastole in all patients by TDI, to assess left ventricular function. Results:1. There are three peaks in all patients include systolic velocity(Vs),early diastolic velocity(Ve),late diastolic velocity(Va).2. Using color Doppler echocardiography, LV structural parameters and systolic parameters had no change between two groups. LV filling parameter were significantly different in the CAD,peak velocity of late filling were higher, ratio of early/late filling velocity were lower, but peak velocity of early filling had no change.3. With TDI mitral annular motion velocity was measured. There were significantly different in mitral annular peak early diastolic velocity (Ve),peaklate diastolic velocity(Va),and ratio of peak early/late diastolic velocity, except systolic velocity(Vs).4. With TDI myocardial wall velocity was measured. There were significantlydifferent in peak early diastolic velocity (Ve),peak late diastolic velocity(Va),and ratio of peak early/late diastolic velocity, except systolic velocity(Vs).5. TDI also can image the regional myocardial systolic velocity especially in ischemic myocardium.Conclusions:1. Our study shows that TDI is a simple, correct and practical method in evaluation of left ventricular diastolic function, regional diastolic function in ischemic myocardium.2. There are difference in left ventricular diastolic function, regional systolicand diastolic function between CAD and Con-groups.3. TDI can be used in no-intervention diagnosing CAD.