Clinical Analysis On Diagnosis And Treatment Of 12cases Of Primary Peritoneal Serous Papillary Carcinoma

Objective: To investigate the clinical features, diagnostic criterion, treatment and prognosis of primary peritoneal serous papilly carcinoma.Methods: Twelve cases of histologically confirmed primary peritoneal serous papillary carcinoma treated in our hospital from 1997 to 2004were retrospectively analyzed.Results: In this series, all patients unederwent cytoreductive surgery and platin-based chemotherapy .The patients who survived for more than 20 months received more than six cycles of chemotherapy. The patients received chemotherapy before surgery survived for more than 28.3 months,which was longer than those without chemotherapy beford surgery.Conclusions: Primary peritoneal serous papillary carcinoma is a rare tumor and difficult to be diagnosed preoperatively. The survival rate can be improved by the definite diagnosis, chemotherapy before surgery, optimal cytoreductive surgery and completed platin-based dchemotherapy . CA₁₂₅ can be one of surveillant markers of this disease.