Effects Of Aerobics And Nutritional Interven On The Carbohydrate Metabolism And Lipid Metabolism In Type 2 Diabetes Mellitus Rats

Obejective: To establish the SD rats model conforms to 2 diabetes characteristics, To observe 2 diabetes rats sugar fat metabolism disorder and the insulin resistance influence by aerobic exercise and the Puerarin supplemented. And to discuss the scientific of 2 diabeteses theories by aerobic exercise and the medicine supplemented.Methods: SD rats were modeled into T2DM rats by high quality of heat feeding for 4weeks and abdominal injection of streptozotocin, then were randomly divided into 5groups:In addition to the normal contrast group, The DM model group was given no treatment; the DM sports group, the DM medicine group and the sports medicine group were respectively treated by aerobic exercise, Puerarin and aerobic exercise+Puerarin. The groups were recorded at which were before the beginning of the treatment, 6 treatment weeks later. The level of FBG, serum insulin, serum FFA, serum TG, serumTC, serum HDL-C, serum LDL-C was measured; and insulin sensitivity index(ISI) was calculated. Results: The method was proved practical that SD rats were modeled into T2DM rats by high quality of heat feeding and abdominal injection of streptozotocin. After experiment, The DM rats FBG, TC, TG, LDL-C, FFA have a decline and there is remarkable difference(P<0.05), The INS, HDL-C have a ascend trend, and there is remarkable difference(P<0.05).As far as the group DM sports+DM medicine is concerned, contrasted by DM model group, Its TC, TG , FFA, FBG and INS have a huge decline and there is very remarkable difference (P<0.01), Its LDL-C have a little decline (P<0.05), While Its HDL-C, ISI and INS have a huge ascend and there is remarkable difference (P<0.01).contrasted by normal group, Its FBG have a little ascend, Its INS have a little decline (P<0.05), but they are closed to normal value;While its ISI have a huge ascend (P<0.01).Therefore, we can make a conclusion that aerobic exercise and the Puerarin supplemented can ameliorate 2 diabetes rats sugar, the fat metabolism disorder and the insulin resistance influence, and can improve carbohydrate metabolism and lipid metabolism to some extent.