A Study Of Influential Factors On Syndrome And Syndrome Normalization On Hyperplasia Of The Mammary Glands

1 ObjectiveThe purpose of this study was to explore the syndrome influential factors and distributive regulation of TCM on hyperplasia of the mammary glands, and to establish foundation of diagnostic standardization on syndromes which is more objective, applicable and operable.2 Method600 outpatients with hyperplasia of the mammary glands (HMG) were observed by four physical examinations in cross-sectional research. Their symptoms and signs were collected to establish initial diagnostic standardization on syndromes by describing analysis , chi square test, rank test , cluster analysis , test of normality and etc.3 ResultsThe study showed that district, age, education and marriage have close relationship with distribution of syndromes, and the difference was significant (P<0. 05) , which was analyzed by chi square test .And there was no evidence manifested that work, working time, economy, inhabited environment had relationship with distribution of syndromes ( P<0.05 ) .With individual-factor analysis, primiparity age, menstrual cycle, gravidity, induced abortion frequency, and time of taking anticoncipiens had close relationship with distribution of syndromes (P<0.05) .But menarche age, menstruation, parity, spontaneous abortion frequency had no relationship with distribution of syndromes (P>0.05) . In anamnesis, uterus myoma, hyropathy had close relationship with distribution of syndromes (P<0. 05) , but ovarian cyst, otherovarian cyst, other mastopathy, mastopathy family history had no relationship with distribution of syndromes (P>0.05). On blood-serum sex hormone indexes, pregnancy hormone and estrogenic hormone had closerelationship with distribution of syndromes ( P<0.05 ) , but prolactin luteinizing hormone, luteinizing hormone and follicle stimulating hormone had no relationship with distribution of syndromes (P>0. 05) . The cluster analystic results of information by four physical examinations were compared with clinic classification of syndrome, and the total coincidence was 38. 83% 0 The test of normality of score distribution on indexes of four physical examinations of every syndrome hinted that: the score distribution of chong ren shi tiao syndrome accorded with mormal distribution, but the score distribution of tan yu hu jie syndrome and gan yu qi zhi syndrome showed skewness distribution, and according to weight of indexes and score distribution , diagnostic reference and score standard of mild, middle and severe degree of every syndrome were obtained by methods of mormal distribution and percentiles. 4 ConclusionThe study explored the relationship between factors which clinic doctors have been interested in and the distribution of syndromes. The results showed that general demographic factors, individual factors, history of past illness and blood-serum sex hormone indexes had close relationship with distribution of syndromes. There was difference between the result of cluster analysis and clinic classification of syndrome, which suggested that the accompanied symptoms are more common than single symptom. The diagnostic reference and score standard of mild, middle and severe degree of every syndrome could provide with initial standardization of quantized diagnose of the syndrome and evaluation of curative effect of TCM.