Study Of Shuanghuanglian Hydrogel

Objective:Upper respiratory infection is one common and frequently encountered disease in pediatrics. Shuang huanglian hydrogel praeparatum are used to cure upper respiratory infection that was caused by influenza-virus,cox-virus,streptococcus. Shuang huanglian is one of curative effect traditional Chinese drug preparations in clinic.Shuanghuanglian suppository is preserved difficultly in summer, suppository is to be melt and deformed in over 30℃conditions, so the quality may be not stable and the effect of clinic may be influenced. However we studied shuanghuanglian Hydrogel in the rectal administered, Hydrogel has many advantages such as bioadhesion, controlled release of medicines, easy to cleaning and uncontaminated clothing. Especially the hydrogel is adapted to the infant and the sufferer that peros medicines difficultly.Method: The crafts did not chaged, because CHP 2005(The people's republic of China Pharmacopoeia 2005).The craft of preparation of Shuanghuanglian hydrogel: Through a synthetical analysis of three Chinese medical herbs, we defined the preparation. We selected 10 hydrogel excipients, such as agar, carbopol, HPMC, CMC-Na, sodium Alginate, Polyvinyl Alcohol-124 and so on to test the preparation of...