Relationship Of MRI Measurement Indexes And Serum Contents Of Immunoglobulins With The Japanese Orthopaedic Association Score For Cervical Function In Patients With Cervical Spondylotic Myelopathy

AIM: To analyze the correlation of MRI measurement indexes and serum contents of immunoglobulins with the Japanese Orthopaedic Association(JOA) score for cervical function in patients with cervical spondylotic myelopathy, and investigate the role autoimmune reaction in the attack duration of cervical spondylotic myelopathy. METHODS: Thirty inpatients and outpatients with cervical spondylotic myelopathy, Who were selected from the Department of sports Medicine, First Affiliated Hospital of AnHui Medical University from June 2004 to March 2005, participated in the study: Acording to the JOA score for cervical function. The patients with cervical spondylotic myelopathy were divided into moderate to severe group (JOA score was 0—12points, n=18), and mild group (JOA score was 13—17points, n=12). Twenty normal people were taken as normal control group. The contents of immunoglobulins(IgG, IgA, IgM) and complement C₃ in serum were detected with scatered turbidimetry in the 30 patients with cervical spondylotic myelopathy, the disc height, sagittal diameters of cord dural sac and spinal, anterior intervertebral space of dural sac were measured. The serum contents of immunoglobulins(IgG, IgA, IgM) and complement C₃ were detected in the 20 cases in the control group. The indexes were compared with the t test and rank sum test.RESULTS: According to intension-to-treat analysis, all the 30 patients with cervical spondylotic myelopathy and 20 normal controls were involved in the analysis of results. â‘  Comparisons of the the disc height, sagittal diameters of cord dural sac and spinal,...