Objective: To investigate the different effect of Fructus Schisandrae Chinensis, Fructus Schisandrae Chinensis add ginger, jujube and sishen pill on spleen deficiency diarrhea and immunity.Methods: 7 groups' rats of spleen deficiency diarrhea were founded as samples to see how they react to prescriptions with different percentage of plasma Mtl, Gas and etc, observing varieties of intestinal propulsion rate; determining the thymus gland and spleen weights of those bigger rats.Results: The guideline of each group is (p<0.01) which indicate that rhubarb can cause spleen deficiency diarrhea; (1) And Fructus Schisandrae Chinensis, Fructus Schisandrae Chinensis add ginger, jujube and sishen pill can stop diarrhea. (2) Mtl and Gas of those under treatment are obviously increased; (3) so was the amount of SIgA, thymus gland and spleen weights; (4) Diarrhea. Fructus Schisandrae Chinensis can also be restrained for those who under treatment.Conclusion: Fructus Schisandrae Chinensis add ginger, jujube and sishen pill can all cure diarrhea and improve immunity by adjusting Mtl and Gas, raising SIgA and increasing IL-2. They can also increase the thymus gland and spleen weights of those rats in experiment. However the different effect could be the following reasons: (1) Sishen pill (decoction) is best for increasing the content of Mtl and Gas, IL-2 and restrained intestinal propulsion, which related to the Fructus Schisandrae Chinensis and ershen pill. (2) Fructus Schisandrae Chinensis do not have the same effect as sishen decoction does in increasing the content of Mtl, Gas and intestinal propulsion. (3) Ginger and jujube can not increase the content of Mtl, Gas and intestinal propulsion alone. (4) Ginger and jujube play an important role in increasing the content of IL-2, SIgA.
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